≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at 2-8°C,Protected from light,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral
Demethylcantharidate disodium, an endogenous metabolite , induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer.
In Vitro
Demethylcantharidate (0-100 μM; 0, 12, 24, 48 or 72 hours) disodium inhibits HCC cell proliferation. Demethylcantharidate (0, 9, 18 or 36 µM; 24 hours) disodium dose dependently increases the levels of cleaved caspase-3, cleaved caspase-9, and Bax/Bcl-2. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: HCC cell lines (SMMC-7721 and Bel-7402) Concentration: 0-100 μM Incubation Time: 0, 12, 24, 48 or 72 hours Result: Showed anti-proliferative activity in the two HCC cell lines. Cell Viability AssayCell Line: HCC cells Concentration: 0, 9, 18 or 36 µM Incubation Time: 24 hours Result: Induced apoptosis in HCC cells via the intrinsic pathway.
In Vivo
Demethylcantharidate disodium significantly decreases hepatocellular carcinoma tumorigenesis of SMMC-7721 cells in vivo . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Specifications
Especificações e pureza
≥98%
Mecanismos bioquímicos e fisiológicos
Demethylcantharidate disodium, an endogenous metabolite , induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer.
Condições de armazenamento de armazenamento
Store at 2-8°C,Protected from light,Desiccated
Enviado em
Wet ice
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Pureza
≥98%
Nomes e identificadores
SMILES isoméricas
C1CC2C(C(C1O2)C(=O)O)C(=O)O.[Na+].[Na+]
PubChem CID
162368041
Peso molecular
230.13
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
H2O : 33.33 mg/mL (144.83 mM; ultrasonic and warming and heat to 60°C) DMSO : <1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)
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