≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
🌡
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
📋
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
📚
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral
Deoxyelephantopin, a natural bioactive sesquiterpene lactone from Elephantopus scaber , has shown promising anticancer effects against a broad spectrum of cancers. Deoxyelephantopin inhibits NF-κB , MAPK , PI3K/Akt , and β-catenin signaling
In Vitro
Deoxyelephantopin inhibits the cell growth of HCT 116 (colorectal), K562 (chronic myeloid leukemia), KB (oral), and T47D (breast) cancer cell lines with IC 50 s of 7.46, 4.02, 3.35, 1.86 μg/mL, respectively. Deoxyelephantopin increases the expression of p53, p-JNK, and p-p38 and decreases the expression of p-STAT3 and p-mTOR in cancer cells. Deoxyelephantopin downregulates MMP-2 and MMP-9, uPA, and uPAR mRNA levels in cancer cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:NF-κB
Specifications
Especificações e pureza
≥99%
Mecanismos bioquímicos e fisiológicos
Deoxyelephantopin, a natural bioactive sesquiterpene lactone from Elephantopus scaber , has shown promising anticancer effects against a broad spectrum of cancers. Deoxyelephantopin inhibits NF-κB , MAPK , PI3K/Akt , and β-catenin signaling.
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Usamos cookies para garantir o funcionamento adequado do site e, quando permitido, para melhorar a sua experiência. Você pode gerenciar suas preferências a qualquer momento nas Configurações. Saiba mais em nossa Política de Cookies.
Deseja que lhe enviemos uma mensagem quando tivermos descontos disponíveis?
Lembrar-me mais tarde
Obrigado! Por favor, verifique a sua caixa de entrada de e-mail para confirmar.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
