emzeltrectinib - Moligand™ , Inhibitor of Janus kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3, CAS No.2223678-97-3, Inhibitor of Janus kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3

CAS: 2223678-97-3 Cat. No.: E610115 PubChem CID: 134480550

GRADE & PURITY Moligand™

Synonyms

GLXC-26845 | GTPL12377 | emzeltrectinib [INN] | 436Z4BZ8HF | SCHEMBL20119394 | 2223678-97-3 | Emzeltrectinib | Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 2-amino-5-[(2R,4S)-2-(2,5-difluorophenyl)-4-fluoro-1-pyrrolidinyl]- | 2-Amino-5-[(2R,4S)-2-(2,5-difluor

Storage

Room temperature

Specifications

Sinónimos

GLXC-26845 | GTPL12377 | emzeltrectinib [INN] | 436Z4BZ8HF | SCHEMBL20119394 | 2223678-97-3 | Emzeltrectinib | Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 2-amino-5-[(2R,4S)-2-(2,5-difluorophenyl)-4-fluoro-1-pyrrolidinyl]- | 2-Amino-5-[(2R,4S)-2-(2,5-difluor

Especificações e pureza

Moligand™

Condições de armazenamento de armazenamento

Room temperature

Grau

Moligand™

Tipo de ação

INHIBITOR

Mecanismo de ação

Inhibitor of Janus kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3

Nomes e identificadores

• Sorrisos canónicos: C1[C@@H](CN([C@H]1c1c(ccc(c1)F)F)c1nc2c(c(nn2cc1)N)C(=O)N)F
• IUPAC Name: 2-amino-5-[(2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
• InChIKey: YFTARXQOKASKBW-JOYOIKCWSA-N
• INCHI: 1S/C17H15F3N6O/c18-8-1-2-11(20)10(5-8)12-6-9(19)7-25(12)13-3-4-26-17(23-13)14(16(22)27)15(21)24-26/h1-5,9,12H,6-7H2,(H2,21,24)(H2,22,27)/t9-,12+/m0/s1
• SMILES isoméricas: C1[C@@H](CN([C@H]1C2=C(C=CC(=C2)F)F)C3=NC4=C(C(=NN4C=C3)N)C(=O)N)F
• PubChem CID: 134480550

Alvos associados (humanos)

NTRK2 Tclin BDNF/NT-3 growth factors receptor (0 Activities)

Discover Target: NTRK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NTRK1 Tclin High affinity nerve growth factor receptor (0 Activities)

Discover Target: NTRK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NTRK3 Tclin NT-3 growth factor receptor (0 Activities)

Discover Target: NTRK3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

JAK2 Tclin Tyrosine-protein kinase JAK2 (0 Activities)

Discover Target: JAK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Perguntas frequentes

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2223678-97-3. InChIKey YFTARXQOKASKBW-JOYOIKCWSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.