Eniporide hydrochloride - 10mM in DMSO , CAS No.211813-86-4

CAS: 211813-86-4 Cat. No.: E655386 Fórmula: C₁₄H₁₇ClN₄O₃S Peso molecular: 356.83 PubChem CID: 9950616

GRADE & PURITY 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na + /H + exchange inhibitor.

In Vitro

There is no significant effects of the Na + /H + exchange inhibitor eniporide on cardiac performance and high energy phosphate content in healthy pig hearts subjected to ischemia/reperfusion induced by crystalloid cardioplegic arrest. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

In stage 1, the administration of 100 mg and 150 mg eniporide results in smaller infarct sizes, especially in the angioplasty group. In contrast, in stage 2 there is no difference in the enzymatic infarct size between the three groups. Overall there is no effect of eniporide on clinical outcome (death, cardiogenic shock, heart failure, life-threatening arrhythmias). However, there is a significant reduction of the incidence of heart failure in patients reperfused late (>4 h). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Sodium Channel

Specifications

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na + /H + exchange inhibitor.

Condições de armazenamento de armazenamento

Desiccated,Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Nomes e identificadores

• SMILES isoméricas: CC1=CC(=C(C=C1C(=O)N=C(N)N)S(=O)(=O)C)N2C=CC=C2.Cl
• PubChem CID: 9950616
• Peso molecular: 356.83