Erythromycin Ethylsuccinate - 10mM in DMSO , Bacterial 70S ribosome inhibitor, CAS No.1264-62-6, Bacterial 70S ribosome inhibitor

CAS: 1264-62-6 Cat. No.: E408903 Fórmula: C₄₃H₇₅NO₁₆ Peso molecular: 862.05 Número CE: 215-033-8

GRADE & PURITY 10mM in DMSO

Synonyms

Erythromycin, 2-(ethyl butanedioate)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Information

Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced byStreptomyces erythreus, reversibly binds to the50S ribosomeof bacteria, and inhibits protein synthesis.
In vitro

Erythromycin displays antibacterial activity against Staphylococcus aureus, streptococcus pneumonia, Streptococcus pyogenes, Haemophilus influenza, Moraxella catarrhalis, Bordetella pertussis, Neisseria gonorrhoeae, Campylobacter jejuni, Helicobacter pylori, and Borrelia burgdorferi. Erythromycin is a motilin receptor agonist, which is a potent stimulator of gastrointestinal motor activity. The concentrations of Erythromycin required to induce 50% of the maximum contractile response to a supramaximal dose of acetylcholine is 2 μM. The concentrations of Erythromycin required to displace 50% of the labeled motilin is 13 μM. Erythromycin has no effect on muscle strips of rat or dog duodenum but induces contractions in human strips.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:

Specifications

Sinónimos

Erythromycin, 2-(ethyl butanedioate)

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Mecanismo de ação

Bacterial 70S ribosome inhibitor

Propriedades do produto

ALogP

3.4

Nomes e identificadores

SMILES isoméricas

CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)OC(=O)CCC(=O)OCC)(C)O)C)C)O)(C)O

WGK Alemanha

2

RTECS

WM9800000

Peso molecular

862.05

Reaxy-Rn

28936360

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28936360&ln=

Perguntas frequentes

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1264-62-6, the molecular formula is C43H75NO16, and the molecular weight is 862.05 g/mol.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.