Laboratory Protocols & SOPs Library

G protein-coupled receptor pathway: GC-cGMP-PKG

· Published 24/12/2024 · Updated 09/06/2025

Summary

Extracellular signals are received by receptors and delivered to AC via Gs or Gi to activate or inhibit it; AC is activated to produce cAMP, which activates PKA, phosphorylating proteins and generating a cellular response; cAMP is hydrolyzed by PDE and the signal is terminated.

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Da — when not otherwise indicated, molecular weight units are daltons. Mw — weight-average molecular weight. Mn — number-average molecular weight.

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Aladdin Scientific. "G protein-coupled receptor pathway: GC-cGMP-PKG" Aladdin Knowledge Base, updated 09/06/2025. https://www.aladdinsci.com/us_pt/faqs/g-protein-coupled-receptor-pathway-gc-c-en.html

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