Farampator - ≥98% , Glutamate receptor ionotropic AMPA positive allosteric modulator, CAS No.211735-76-1, Glutamate receptor ionotropic AMPA positive allosteric modulator

CAS: 211735-76-1 Cat. No.: F412201 Fórmula: C₁₂H₁₃N₃O₂ Peso molecular: 231.25

GRADE & PURITY ≥98%

Synonyms

Piperidine, 1-(2,1,3-benzoxadiazol-5-ylcarbonyl)- | Q5434818 | 7X6P5N8K2L | Org24448 | Org-24448 | BCP28990 | A935040 | AC-36657 | CX691;1-(benzofurazan-5-ylcarbonyl)piperidine | CX-691;Org24448 | EX-A4789 | 2,1,3-benzoxadiazol-5-yl(piperidin-1-yl)methano

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

Information

Farampator (CX691, Org24448) is a positive modulator of AMPA receptor.

Specifications

Sinónimos

Piperidine, 1-(2,1,3-benzoxadiazol-5-ylcarbonyl)- | Q5434818 | 7X6P5N8K2L | Org24448 | Org-24448 | BCP28990 | A935040 | AC-36657 | CX691;1-(benzofurazan-5-ylcarbonyl)piperidine | CX-691;Org24448 | EX-A4789 | 2,1,3-benzoxadiazol-5-yl(piperidin-1-yl)methano

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

Farampator (CX691, Org24448) is a positive modulator of AMPA receptor.

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

POSITIVE ALLOSTERIC MODULATOR

Mecanismo de ação

Glutamate receptor ionotropic AMPA positive allosteric modulator

Pureza

≥98%

Propriedades do produto

• ALogP: 1.5

Nomes e identificadores

• Pubchem Sid: 504762853
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504762853
• Sorrisos canónicos: C1CCN(CC1)C(=O)C2=CC3=NON=C3C=C2
• IUPAC Name: 2,1,3-benzoxadiazol-5-yl(piperidin-1-yl)methanone
• InChIKey: XFVRBYKKGGDPAJ-UHFFFAOYSA-N
• INCHI: 1S/C12H13N3O2/c16-12(15-6-2-1-3-7-15)9-4-5-10-11(8-9)14-17-13-10/h4-5,8H,1-3,6-7H2
• SMILES isoméricas: C1CCN(CC1)C(=O)C2=CC3=NON=C3C=C2
• Peso molecular: 231.25
• Reaxy-Rn: 13677286
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13677286&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Piperidines
      • Subclass N-acylpiperidines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Piperidines
• Subclass: N-acylpiperidines
• Intermediate Tree Nodes: Not available
• Direct Parent: N-benzoylpiperidines
• Alternative Parents: Benzoxadiazoles Benzenoids Tertiary carboxylic acid amides Heteroaromatic compounds Furazans Oxacyclic compounds Azacyclic compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: N-benzoylpiperidine - Benzoxadiazole - Benzenoid - Azole - Furazan - Heteroaromatic compound - Oxadiazole - Tertiary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Oxacycle - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as n-benzoylpiperidines. These are heterocyclic Compounds containing a piperidine ring conjugated to a benzyl group through one nitrogen ring atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

GRIA4 Tclin Glutamate receptor AMPA 3/4 (3 Activities)

Discover Target: GRIA4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Propriedades químicas e físicas

• Peso molecular: 231.250 g/mol
• XLogP3: 1.500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 231.101 Da
• Monoisotopic Mass: 231.101 Da
• Topological Polar Surface Area: 59.200 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 291.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 211735-76-1, the molecular formula is C12H13N3O2, and the molecular weight is 231.25 g/mol. InChIKey XFVRBYKKGGDPAJ-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.