GLP-1R agonist 2 - ≥98% , CAS No.281209-71-0

CAS: 281209-71-0 Cat. No.: G646480 Fórmula: C₁₃H₁₅Cl₂N₃O₂S Peso molecular: 348.25 Número CE: 803-650-0 PubChem CID: 16007289

GRADE & PURITY ≥98%

Synonyms

HY-121835 | GLP-1R agonist DMB | N-tert-butyl-6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-amine | N-(tert-Butyl)-6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-amine | GLP-1R agonist | SCHEMBL2555049 | GLP-1R agonist 2 | HMS3740K03 | GLP1-agonist-2 | E98852

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

GLP-1R agonist 2 (compound 2) is a potent GLP-1R agonist. GLP-1R agonist 2 has the potential for the research of metabolic diseases like Type2 Diabetes and Obesity.

Form:Solid

Specifications

Sinónimos

HY-121835 | GLP-1R agonist DMB | N-tert-butyl-6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-amine | N-(tert-Butyl)-6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-amine | GLP-1R agonist | SCHEMBL2555049 | GLP-1R agonist 2 | HMS3740K03 | GLP1-agonist-2 | E98852

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

GLP-1R agonist 2 (compound 2) is a potent GLP-1R agonist. GLP-1R agonist 2 has the potential for the research of metabolic diseases like Type2 Diabetes and Obesity.

Condições de armazenamento de armazenamento

Protected from light,Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

AGONIST

Pureza

≥98%

Nomes e identificadores

• Pubchem Sid: 528764608
• Sorrisos canónicos: CC(C)(C)NC1=NC2=CC(=C(C=C2N=C1S(=O)(=O)C)Cl)Cl
• IUPAC Name: N-tert-butyl-6,7-dichloro-3-methylsulfonylquinoxalin-2-amine
• InChIKey: GNZCSGYHILBXLL-UHFFFAOYSA-N
• INCHI: 1S/C13H15Cl2N3O2S/c1-13(2,3)18-11-12(21(4,19)20)17-10-6-8(15)7(14)5-9(10)16-11/h5-6H,1-4H3,(H,16,18)
• SMILES isoméricas: CC(C)(C)NC1=NC2=CC(=C(C=C2N=C1S(=O)(=O)C)Cl)Cl
• WGK Alemanha: 3
• PubChem CID: 16007289
• Peso molecular: 348.25

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Diazanaphthalenes
      • Subclass Benzodiazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Diazanaphthalenes
• Subclass: Benzodiazines
• Intermediate Tree Nodes: Not available
• Direct Parent: Quinoxalines
• Alternative Parents: Aminopyrazines Imidolactams Benzenoids Aryl chlorides Sulfones Heteroaromatic compounds Azacyclic compounds Organochlorides Organic oxides Hydrocarbon derivatives Amines
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Quinoxaline - Aminopyrazine - Aryl chloride - Aryl halide - Pyrazine - Imidolactam - Benzenoid - Heteroaromatic compound - Sulfonyl - Sulfone - Azacycle - Hydrocarbon derivative - Organosulfur compound - Organonitrogen compound - Organochloride - Organohalogen compound - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as quinoxalines. These are compounds containing a quinoxaline moiety, a bicyclic heterocycle made up of a benzene ring fused to a pyrazine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

GLP1R Tclin Glucagon-like peptide 1 receptor (2 Activities)

Discover Target: GLP1R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: DMSO : 25 mg/mL (71.79 mM; ultrasonic and warming and heat to 60°C)
• Sensibilidade: Light sensitive
• Peso molecular: 348.200 g/mol
• XLogP3: 3.900
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 347.026 Da
• Monoisotopic Mass: 347.026 Da
• Topological Polar Surface Area: 80.300 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 475.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referências

1. Xin Sun, Jiangnan Hu, Maomao Ren, Hong Chang, Dongting Zhangsun, Baojian Zhang, Shuai Dong.  (2024)  Stapling Cysteine[2,4] Disulfide Bond of α-Conotoxin LsIA and Its Potential in Target Delivery.  Marine Drugs,      [PMID:39057423] [10.3390/md22070314]

2. Jinnai Liu, Jiawei Tang, Hao Chen, Li Zhang, Ganlan Li, Fuli Zhang, Shaoxin Chen, Jun Yu.  (2026)  Highly Enantioselective Chemoenzymatic and Kilogram-Scale Process Development of (S)-3-Bromo-2-(1-methoxyethyl)pyridine.  ORGANIC PROCESS RESEARCH & DEVELOPMENT,      [PMID:] [10.1021/acs.oprd.5c00349]

3. Jidong Jia, Jia Liu, YinLin Lu, Hang Zuo, Xingzhi Wu, Yinglin Song.  (2026)  Optimizing nonlinear absorption via modulating π-electron delocalization in multi-ring conjugated cores: from TPA at 515/650 nm to broad temporal response.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:] [10.1016/j.saa.2026.128604]