HeE1-2Tyr - ≥96% , CAS No.2245195-67-7

CAS: 2245195-67-7 Cat. No.: H649577 Fórmula: C33H30N2O6S Peso molecular: 582.67
Disponível para encomenda
GRADE & PURITY ≥96%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
USA
Alemanha (EU)*
Price
Qty
5mg
H649577-5mg
Sob encomenda · 8–12 semanas
500,90US$
10mg
H649577-10mg
Sob encomenda · 8–12 semanas
800,90US$
25mg
H649577-25mg
Sob encomenda · 8–12 semanas
1700,90US$
50mg
H649577-50mg
Sob encomenda · 8–12 semanas
2700,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

≥96% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. HeE1-2Tyr significantly inhibits West Nile , Dengue and SARS-CoV-2 RdRps ( IC 50 of 27.6 µM) activity in vitro

In Vitro

HeE1-2Tyr shows antiviral activity, it is able to inhibit an Ugandan strain of West Nile virus with an IC 50 of 2.1 µM, as well as all the four Dengue virus (DENV) serotypes, with IC 50 ranging from 6.8 to 15 µM. The cytotoxicity of HeE1-2Tyr versus Vero E6 cells is ~115 µM. Additionally, upon infection of human HEK 293 cells (CC 50 of 50 µM), HeE1-2Tyr inhibits clinical strains of yellow fever virus with IC 50 values ranging from 3.9 to 12 µM. HeE1-2Tyr completely inhibits the replication of both SARS-CoV-2 and Feline coronavirus (FIPV). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Flavivirus RNA dependent RNA polymerases (RdRp), SARS-CoV-2 RdRps>

Specifications

Especificações e pureza
≥96%
Mecanismos bioquímicos e fisiológicos
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. HeE1-2Tyr significantly inhibits West Nile , Dengue and SARS-CoV-2 RdRps ( IC 50 of 27.6 µM) activity in vitro.
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Tipo de ação
INHIBITOR
Pureza
≥96%
Nomes e identificadores
Peso molecular 582.67

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriedades químicas e físicas
SolubilidadeDMSO : 100 mg/mL (171.62 mM; Need ultrasonic)
Calculadoras de soluções
Revisões

Avaliações dos Clientes

Perguntas frequentes

What is the purity of this product?
This product is supplied at ≥96% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 2245195-67-7, the molecular formula is C33H30N2O6S, and the molecular weight is 582.67 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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