MAb de ratinho HEXIM1 - Anticorpo primário, specific to HEXIM1, Mouse IgG2a

Cat. No.: Ab107363

GRAU & PUREZA Carrier Free, ExactAb™, Validated, 1.0 mg/mL

Application

WB

Host species

Rato

Reactive species

Humano, Rato

Isotype

Mouse IgG2a

Clone Number

K40046_16G4

Conjugation

Unconjugated

Visão geral

O anticorpo anti-HEXIM1 humano de ratinho, monoclonal (K40046_16G4), pode ser utilizado para WB e assim por diante.
Aplicação:
WB: 1/1000
Função da proteína:
Regulador transcricional que funciona como um inibidor geral da transcrição da RNA polimerase II. Em cooperação com o snRNA 7SK, sequestra o P-TEFb num grande complexo inativo de snRNP 7SK, impedindo a fosforilação da RNA polimerase II e o subsequente alongamento da transcrição. Pode também regular a atividade transcricional dependente de NF-kappa-B, ESR1, NR3C1 e CIITA.

Especificações

Product Name

MAb de ratinho HEXIM1 - Anticorpo primário, specific to HEXIM1, Mouse IgG2a

Sinónimos

Anticorpo para a proteína 1 da linhagem cardíaca | anticorpo CLP 1 | anticorpo CLP1 | anticorpo EDG 1 | anticorpo EDG1 | anticorpo para a proteína 1 do gene regulado para baixo dos estrogénios | anticorpo FLJ13562 | anticorpo induzível por hexametileno bi

Especificações e pureza

ExactAb™, validado, sem suporte, 1,0 mg/mL

Espécie hospedeira

Rato

Especificidade

HEXIM1

Imunogénio

Recombinant human HEXIM1 (AA 141-340).

Controlo positivo

WB: HeLa, LNCaP and C6 cell lysates.

Conjugação

Unconjugated

Grau

Carrier Free, ExactAb™, Validated

Isótipo

Mouse IgG2a

Tipo de corrente de luz

kappa

SDS-PAGE

150 kDa

Método de purificação

Protein A purified

Concentração

1.0 mg/mL

Product Line

Produtos biológicos

Armazenamento e envio

Forma

Líquido

Condições de armazenamento de armazenamento

Conservar a -80°C. Evitar a congelação e descongelação repetidas

Enviado em

Dry ice packs + Cold packs

Estabilidade e armazenamento

Armazenar a 2-8 ℃ (3 meses). Armazenar a -20 ℃ (12 meses). Armazenar a -80 ℃ (36 meses). Após a receção, recomenda-se a aliquotagem. Evitar o ciclo de congelamento/descongelamento.

Imagens

Western Blot: HEXIM1 Mouse mAb (Ab107363)

HEXIM1 Mouse mAb (Ab107363) - Western Blot
All lanes: HEXIM1 Mouse mAb (Ab107363) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/10000 dilution

Predicted band size: 41 kDa
Observed band size: 55 kDa
Exposure time: 120.0 s

Western Blot: HEXIM1 Mouse mAb (Ab107363)

HEXIM1 Mouse mAb (Ab107363) - Western Blot
All lanes: HEXIM1 Mouse mAb (Ab107363) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/10000 dilution

Predicted band size: 41 kDa
Observed band size: 55 kDa
Exposure time: 30.3 s

Aplicação

Aplicação

Dilution info

WB

1/1000

Alvos associados (humanos)

HEXIM1 Tbio Protein HEXIM1 (0 Activities)

Discover Target: HEXIM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de ação

Perguntas frequentes

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (HEXIM1 Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.