IEM 1925 dihydrobromide - ≥95% , CAS No.258282-23-4

CAS: 258282-23-4 Cat. No.: I288059 Fórmula: C₁₇H₂₈N₂•2HBr Peso molecular: 422.24 PubChem CID: 44561101

GRAU & PUREZA ≥95%

Synonyms

N-(1-Phenylcyclohexyl)-1,5-pentanediamine dihydrobromide

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Visão geral

AMPA receptor antagonist

Especificações

Sinónimos

N-(1-Phenylcyclohexyl)-1,5-pentanediamine dihydrobromide

Especificações e pureza

≥95%

Mecanismos bioquímicos e fisiológicos

Voltage- and use-dependent open-channel antagonist of AMPA receptors. Selective between subtypes; blocks GluA2 subunit-lacking receptors more potently than GluA2-containing receptors (KDfor GluA2-containing AMPAR is 210 times higher at -80 mV). More poten

Condições de armazenamento de armazenamento

Store at -20°C,Argon charged,Desiccated

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

ANTAGONIST

Pureza

≥95%

Nomes e identificadores

Pubchem Sid

528764875

Sorrisos canónicos

C1CCC(CC1)(C2=CC=CC=C2)NCCCCCN.Br.Br

IUPAC Name

N'-(1-phenylcyclohexyl)pentane-1,5-diamine;dihydrobromide

InChIKey

ZCYUSVRXEKAQSL-UHFFFAOYSA-N

INCHI

1S/C17H28N2.2BrH/c18-14-8-3-9-15-19-17(12-6-2-7-13-17)16-10-4-1-5-11-16;;/h1,4-5,10-11,19H,2-3,6-9,12-15,18H2;2*1H

SMILES isoméricas

C1CCC(CC1)(C2=CC=CC=C2)NCCCCCN.Br.Br

PubChem CID

44561101

Peso molecular

422.24

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Classe Organonitrogen compounds
      • Subclass Amines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Classe: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Not available
• Direct Parent: Aralkylamines
• Alternative Parents: Cyclohexylamines Benzene and substituted derivatives Dialkylamines Monoalkylamines Hydrocarbon derivatives Hydrobromides
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Aralkylamine - Cyclohexylamine - Benzenoid - Monocyclic benzene moiety - Secondary amine - Secondary aliphatic amine - Hydrocarbon derivative - Hydrobromide - Primary amine - Primary aliphatic amine - Aromatic homomonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: Solvent:water, Max Conc. mg/mL: 42.22, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 21.11, Max Conc. mM: 50
• Peso molecular: 422.200 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 422.076 Da
• Monoisotopic Mass: 420.078 Da
• Topological Polar Surface Area: 38.100 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 227.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3