IFN-γ mAb de ratinho - Anticorpo primário, specific to Interferon gamma, Mouse IgG1

Cat. No.: Ab110987

GRADE & PURITY Carrier Free, Validated, ExactAb™, Azide Free, PBS Only, ≥95%(SDS-PAGE), See COA

Application

Animal Model, Flow Cytometry, Functional Assay, Neutralization

Host species

Rato

Reactive species

Humano

Isotype

Mouse IgG1

Clone Number

B133.5

Conjugation

Unconjugated

Visão geral

O anticorpo anti-interferão gama humano de ratinho, monoclonal (B133.5), pode ser utilizado para a neutralização in vivo de IFNγ em ratinhos humanizados, neutralização in vitro de IFNγ, fluxo e assim por diante.
Aplicação:
neutralização in vivo de IFNγ em ratinhos humanizados: Utilizar numa concentração dependente do ensaio.
neutralização in vitro de IFNγ: Utilizar numa concentração dependente do ensaio.
Fluxo: Utilizar numa concentração dependente do ensaio.
Função da proteína
Produzido por linfócitos activados por antigénios específicos ou mitogénios. O IFN-gama, para além de ter atividade antivírica, tem importantes funções imunoreguladoras. É um potente ativador de macrófagos, tem efeitos antiproliferativos em células transformadas e pode potenciar os efeitos antivirais e antitumorais dos interferões de tipo I.

Specifications

Product Name

IFN-γ mAb de ratinho - Anticorpo primário, specific to Interferon gamma, Mouse IgG1

Sinónimos

IFG | IFI | IFNG | IFNgamma | IFN-gama | Interferão imunitário | interferão gama | interferão, gama | anticorpo IF 1 | anticorpo IFG | anticorpo IFI | anticorpo ifn g | anticorpo IFN gama | IMD69 | anticorpo imunitário IFN | IFN, anticorpo imunitário | an

Especificações e pureza

Sem transportador, ExactAb™, sem azida, validado, ≥95% (SDS-PAGE), ver COA

Espécie hospedeira

Rato

Especificidade

Interferon gamma

Imunogénio

Recombinant protein of human IFNγ

Conjugação

Unconjugated

Grau

Azide Free, Carrier Free, ExactAb™, PBS Only, Validated

Isótipo

Mouse IgG1

Tipo de corrente de luz

kappa

SDS-PAGE

150 kDa

Método de purificação

Protein A purified

Concentração

See COA

Armazenamento e envio

Forma

Líquido

Condições de armazenamento de armazenamento

Armazenar a 2-8°C,Congelar proibido

Enviado em

Gelo húmido

Estabilidade e armazenamento

Expedido a 4°C. Conservar a 4°C durante um longo período (12 meses). Não congelar. Após a receção, recomenda-se a aliquotagem.

Imagens

ELISA: IFN-γ Mouse mAb (Ab110987)

IFN-γ Mouse mAb (Ab110987) - ELISA
Immobilized Recombinant Human IFN-gamma protein (rp156182) at 2.0 μg/mL can bind IFN-γ Mouse mAb (Ab110987) with the EC50 of 38.03 ng/mL.

SEC: IFN-γ Mouse mAb (Ab110987)

IFN-γ Mouse mAb (Ab110987) - SEC
The purity of IFN-γ Mouse mAb (Ab110987) is more than 95% verified by HPLC.

Aplicação

• Aplicação: Dilution info
• Flow Cytometry:

  Use at an assay dependent concentration.

• in vivo IFNγ neutralization in humanized mice:

  Use at an assay dependent concentration.;

• in vitro IFNγ neutralization:

  Use at an assay dependent concentration.;

Perguntas frequentes

What is the purity of this product, and how is it determined?

This product is supplied at ≥95% purity, determined by SDS-PAGE. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C. Do not freeze. Freezing may cause irreversible damage to this material.

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (IFN-γ Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.