Recombinant IgdE protease, CAS No.1892548-76-3

CAS: 1892548-76-3 Cat. No.: I1442594
AVAILABLE TO ORDER
GRADE & PURITY Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. ≥95%(HPLC) expressed in E.coli
Expression system
E. coli
Size
USA
Germany (EU)*
Price
Qty
1KU
I1442594-1KU
US Made to order · 2–4 wks ·
$799.90
250U
I1442594-250U
US Made to order · 2–4 wks ·
$279.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

EnzymoPure™, Bioactive, ≥95%(HPLC), expressed in E.coli Bioactive,EnzymoPure™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage.

Specifications

Product Name
Recombinant IgdE protease, CAS No.1892548-76-3
Synonyms
Immunoglobulin G-degrading enzyme | IgdE peptidase | Cysteine protease IgdE
Grade
Bioactive, EnzymoPure™
Specifications & Purity
EnzymoPure™, Bioactive, ≥95%(HPLC), expressed in E.coli
CAS
1892548-76-3
Molecule Type
Enzyme
Storage and Shipping
Concentration
expressed in E.coli
Reconstitution
Reconstitute with water to 40 U/μL.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20℃ long term (12 months). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.
Unit definition
The amount of enzyme required to cleave 1 μg of Human IgG1 (>90%) in 150 mM PB buffer (pH 7.0) at 37 °C for 16–18 hours.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Bioactive grade guide → View EnzymoPure™ grade guide →

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.