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JW 642 is a potent inhibitor of monoacylglycerol lipase ( MAGL ) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.IC50 value: 7.6/14/3.7 nM(mouse/rat/human MAGL ) Target: MAGL inhibitor JW 642 is selective for MAGL , requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s = 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively).
| CAS | 1416133-89-5 |
|---|---|
| Concentração | 10 mM in DMSO |
| Especificações e pureza | Moligand™, 10 mM in DMSO |
| Condições de armazenamento de armazenamento | Argon charged,Store at -80°C |
| Enviado em | Dry ice packs + Cold packs |
| Product Description | JW 642 is a potent inhibitor of monoacylglycerol lipase ( MAGL ) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.IC50 value: 7.6/14/3.7 nM(mouse/rat/human MAGL ) Target: MAGL inhibitor JW 642 is selective for MAGL , requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s = 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively). |