LTV-1 - 10mM in DMSO , CAS No.347379-29-7

CAS: 347379-29-7 Cat. No.: L656738 Fórmula: C₂₆H₂₀N₂O₅S Peso molecular: 472.51 Número CE: 803-585-8 PubChem CID: 1920999

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

LTV-1 is a potent lymphoid tyrosine phosphatase ( LYP ) inhibitor in T cells with an IC 50 of 508 nM. LTV-1 has the potential for autoimmunity treatment

In Vitro

LTV-1 (1.25-40 μM) has no notable effect on cell viability (metabolic rate assay), even at the highest concentration tested (40 μM). Thus, LTV-1 is not cytotoxic in HeLa cells, Jurkat TAg T cells and peripheral blood mononuclear cells (PBMC). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: HeLa cells, Jurkat TAg T cells, and PBMC Concentration: 1.25, 2.5, 5.0, 10, 20 , and 40 μM Incubation Time: 48 hours Result: Had no notable effect on cell viability (metabolic rate assay), even at the highest concentration tested (40 μM).

IC50& Target:IC50: 508 nM (LYP, in T cells)

Specifications

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

LTV-1 is a potent lymphoid tyrosine phosphatase ( LYP ) inhibitor in T cells with an IC 50 of 508 nM. LTV-1 has the potential for autoimmunity treatment.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Nomes e identificadores

• SMILES isoméricas: CC1=CC=CC=C1N2C(=O)/C(=C/C3=CC=C(C=C3)OCC4=CC(=CC=C4)C(=O)O)/C(=O)NC2=S
• PubChem CID: 1920999
• Peso molecular: 472.51

Perguntas frequentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 347379-29-7, the molecular formula is C26H20N2O5S, and the molecular weight is 472.51 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.