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Miconazole - Moligand™, 10mM in DMSO , Cytochrome P450 51 inhibitor, CAS No.22916-47-8, Cytochrome P450 51 inhibitor

Miconazole - Moligand™, 10mM in DMSO , Cytochrome P450 51 inhibitor, CAS No.22916-47-8, Cytochrome P450 51 inhibitor

CAS: 22916-47-8 Cat. No.: M407984 Molecular Weight: 416.14 EC Number: 245-324-5

2 Citations COA

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Miconazole - Moligand™, 10mM in DMSO CAS No(22916-47-8) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY Moligand™ ? 10mM in DMSO

Synonyms

1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview Specifications Product Properties Names and Identifiers Documentation Advanced Data Associated Targets(Human) Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Documents & Articles Citations of This Product References Solution Calculators Reviews

🧪

Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Miconazole Miconazole (Monistat) is an imidazole antifungal agent.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥96%

Specifications

Synonyms

1-[2-(2, 4-dichlorophenyl)-2-[(2, 4-dichlorophenyl)methoxy]ethyl]-1H-imidazole

Specifications & Purity

Moligand™, 10mM in DMSO

Biochemical and Physiological Mechanisms

Miconazole (Monistat) is an imidazole antifungal agent.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

CHANNEL BLOCKER, INHIBITOR

Mechanism of action

Cytochrome P450 51 inhibitor

Product Properties

ALogP	5.3

Names and Identifiers

Isomeric SMILES	C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl
Molecular Weight	416.14
Reaxy-Rn	965511
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=965511&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)

CYP2D6 Tclin Cytochrome P450 2D6 (2 Activities)

Discover Target: CYP2D6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2J2 Tchem Cytochrome P450 2J2 (2 Activities)

Discover Target: CYP2J2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2C19 Tchem Cytochrome P450 2C19 (2 Activities)

Discover Target: CYP2C19

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 (6 Activities)

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP51A1 Tchem Lanosterol 14-alpha demethylase (1 Activities)

Discover Target: CYP51A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 (2 Activities)

Discover Target: CYP2C9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter (2 Activities)

Discover Target: SLC6A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TBXAS1 Tchem Thromboxane-A synthase (1 Activities)

Discover Target: TBXAS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP19A1 Tclin Aromatase (1 Activities)

Discover Target: CYP19A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP17A1 Tclin Steroid 17-alpha-hydroxylase/17,20 lyase (1 Activities)

Discover Target: CYP17A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solubility (25°C) In vitro DMSO: 30 mg/mL (46.11 mM); Water: Insoluble; Ethanol: Insoluble;
Melt Point(°C)	83-97°C

Documents & Articles

Tuning Logic of Imidazole Heteroaromatic Building Blocks: How Dual Nitrogen Sites and Substitution / Salt Forms / Ring Fusion Modulate Charge, Hydrogen Bonding, and Coordination (with Tables A–E)

Categories: Technical articles

Tags:

Imidazole Heteroaromatic Building Blocks

Citations of This Product

How to Cite Aladdin Scientific Products? Citations Search

References

1. Xu Yang-ding, Guo Yu-jie, Mao He-rong, Xiong Zhi-xiang, Luo Meng-yu, Luo Rui-qi, Lu Shan, Huang Lu, Hong Yi. (2023) Integration of transcriptomics and proteomics to elucidate inhibitory effect and mechanism of rosmarinic acid from Perilla frutescens (L.) Britt. in treating Trichophyton mentagrophytes. Chinese Medicine, 18 (1): (1-20). [PMID:37280712] [10.1186/s13020-023-00772-2]
2. Kamran Bashir, Zhimin Luo, Guoning Chen, Hua Shu, Xia Cui, Wen Li, Wang Lu, Qiang Fu. (2019) Development of Surface Molecularly Imprinted Polymers as Dispersive Solid Phase Extraction Coupled with HPLC Method for the Removal and Detection of Griseofulvin in Surface Water. International Journal of Environmental Research and Public Health, 17 (1): (134). [PMID:31878121] [10.3390/ijerph17010134]

Solution Calculators

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Reviews

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