NCX 466 - ≥98%(HPLC) , CAS No.1262956-64-8

CAS: 1262956-64-8 Cat. No.: N288651 Fórmula: C₂₀H₂₄N₂O₉ Peso molecular: 436.41 PubChem CID: 49855334

GRADE & PURITY ≥98%(HPLC)

Synonyms

(αS)-6-Methoxy-α-methyl-2-naphthaleneacetic acid (5S)-5,6-bis(nitrooxy)hexyl ester | (S)-(S)-5,6-bis(nitrooxy)hexyl 2-(6-methoxynaphthalen-2-yl)propanoate

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

Product description：

cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor

Specifications

Sinónimos

(αS)-6-Methoxy-α-methyl-2-naphthaleneacetic acid (5S)-5,6-bis(nitrooxy)hexyl ester | (S)-(S)-5,6-bis(nitrooxy)hexyl 2-(6-methoxynaphthalen-2-yl)propanoate

Especificações e pureza

≥98%(HPLC)

Mecanismos bioquímicos e fisiológicos

Cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor (CINOD). Inhibits COX-1 and COX-2 while releasing NO. Demonstrates higher efficacy than naproxen, its congener drug, in reducing levels of profibrotic cytokine transforming growth factor-βand oxidati

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Pureza

≥98%(HPLC)

Nomes e identificadores

• Sorrisos canónicos: CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)OCCCCC(CO[N+](=O)[O-])O[N+](=O)[O-]
• IUPAC Name: [(5S)-5,6-dinitrooxyhexyl] (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
• InChIKey: QTUSNUCZIUBIBF-LIRRHRJNSA-N
• INCHI: 1S/C20H24N2O9/c1-14(15-6-7-17-12-18(28-2)9-8-16(17)11-15)20(23)29-10-4-3-5-19(31-22(26)27)13-30-21(24)25/h6-9,11-12,14,19H,3-5,10,13H2,1-2H3/t14-,19-/m0/s1
• SMILES isoméricas: C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)OCCCC[C@@H](CO[N+](=O)[O-])O[N+](=O)[O-]
• PubChem CID: 49855334
• Peso molecular: 436.41

Propriedades químicas e físicas

• Solubilidade: Solvent:DMSO, Max Conc. mg/mL: 43.64, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 43.64, Max Conc. mM: 100