p-Chlorobenzaldehyde - ≥98% , CAS No.104-88-1

CAS: 104-88-1 Cat. No.: C104155 Molecular Weight: 140.57 Beilstein Registry Number: 385858 EC Number: 203-247-4
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
PCAD | W-108802 | 4-Chlorbenzaldehyd | MFCD00003379 | D77694 | 4-Chlorobenzaldehyd | 4-Chlorobenzaldehyde | 4-chloro-benzaldehyde | 4-formylchlorobenzene | STR00145 | CHLOROBENZALDEHYDE, 4- | EC 203-247-4 | AI3-52280 | bmse001029 | p-Chlorobenzenecarboxal
Storage
Argon charged,Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25g
C104155-25g
8
$18.90
100g
C104155-100g
4

$24.90

$25.90
Save $1.00 (3.86%)
500g
C104155-500g
3
$49.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 28 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

4-Chlorobenzaldehyde reacts with 3-tert-butyl-N-4-chlorobenzyl-1-phenyl-1H-pyrazol-5-amine to form (E)-3-tert-Butyl-4-(4-chlorobenzyl)-N-(4-chlorobenzylidene)-1-phenyl-1H-pyrazol-5-amine by a microwave-mediated reaction.

Specifications

Synonyms
PCAD | W-108802 | 4-Chlorbenzaldehyd | MFCD00003379 | D77694 | 4-Chlorobenzaldehyd | 4-Chlorobenzaldehyde | 4-chloro-benzaldehyde | 4-formylchlorobenzene | STR00145 | CHLOROBENZALDEHYDE, 4- | EC 203-247-4 | AI3-52280 | bmse001029 | p-Chlorobenzenecarboxal
Specifications & Purity
≥98%
Storage
Argon charged, Room temperature
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid488180542
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180542
Canonical SmilesC1=CC(=CC=C1C=O)Cl
IUPAC Name4-chlorobenzaldehyde
InChIKeyAVPYQKSLYISFPO-UHFFFAOYSA-N
INCHI1S/C7H5ClO/c8-7-3-1-6(5-9)2-4-7/h1-5H
Isomeric SMILES C1=CC(=CC=C1C=O)Cl
WGK Germany 2
RTECS CU5076000
UN Number 2811
Packing Group I
Molecular Weight 140.57
Beilstein 385858
Reaxy-Rn 385858
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=385858&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassBenzoyl derivatives
Intermediate Tree Nodes Not available
Direct ParentBenzoyl derivatives
Alternative Parents Benzaldehydes  Chlorobenzenes  Aryl chlorides  Organochlorides  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Benzoyl - Benzaldehyde - Aryl-aldehyde - Halobenzene - Chlorobenzene - Aryl halide - Aryl chloride - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organochloride - Organohalogen compound - Aldehyde - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as benzoyl derivatives. These are organic compounds containing an acyl moiety of benzoic acid with the formula (C6H5CO-).
External Descriptors monochlorobenzenes - benzaldehydes
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
SLC6A1 Tclin GABA transporter 1 (308 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MPO Tchem Myeloperoxidase (1002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
B16-F10 (4610 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot NumberCertificate TypeDateItem
G2629046Certificate of AnalysisOct 24, 2025 C104155
K2510271Certificate of AnalysisOct 24, 2025 C104155
K2510270Certificate of AnalysisOct 24, 2025 C104155
K2510264Certificate of AnalysisOct 24, 2025 C104155
F2101156Certificate of AnalysisDec 18, 2024 C104155
F2101160Certificate of AnalysisDec 18, 2024 C104155
C2414231Certificate of AnalysisMar 02, 2024 C104155
D2409002Certificate of AnalysisFeb 22, 2024 C104155
D2409003Certificate of AnalysisFeb 22, 2024 C104155
F2101155Certificate of AnalysisMar 10, 2023 C104155
L2028019Certificate of AnalysisOct 18, 2022 C104155
K2217396Certificate of AnalysisAug 15, 2022 C104155
K2217397Certificate of AnalysisAug 15, 2022 C104155
K2217395Certificate of AnalysisAug 15, 2022 C104155
K2217394Certificate of AnalysisAug 15, 2022 C104155
K2217393Certificate of AnalysisAug 15, 2022 C104155
K2217392Certificate of AnalysisAug 15, 2022 C104155

Show more ⌵

Chemical and Physical Properties
SolubilitySoluble in water (0.94g/L).
SensitivityMoisture sensitive;Light and air Sensitive
Refractive Index1.5552
Flash Point(°F)188.6 °F
Flash Point(°C) 87℃
Boil Point(°C)213-214°C
Melt Point(°C)47.5°C
Molecular Weight140.560 g/mol
XLogP32.100
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass140.003 Da
Monoisotopic Mass140.003 Da
Topological Polar Surface Area17.100 Ų
Heavy Atom Count9
Formal Charge0
Complexity95.100
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Yang You, Zheng Yue Wang, Min Zhi Rong, Ming Qiu Zhang.  (2023)  Reversibly Interlocking of Immiscible Covalent Adaptive Networks in Solid State: A Paradigm for Enhancing Interfacial Interaction of Multicomponent Polymer Systems.  MACROMOLECULES,      [PMID:] [10.1021/acs.macromol.3c01632]
2. Hu Tian, Yuanyuan Zhang, Lin Liu, Jinjuan Xing, Xiaojun Wang.  (2023)  Assessment of anti-corrosion behavior of three triazolyl Schiff bases in 3.5 wt% NaCl Solution: Experimental and theoretical approaches.  Materials Today Communications,      [PMID:] [10.1016/j.mtcomm.2023.106937]
3. Lei Yuan, Cai Xu, Shaoyong Zhang, Mincheng Yu, Xiaozhong Wang, Yingqi Chen, Liyan Dai.  (2023)  Role of oxygen vacancy in spinel (FeCoNiCrMn)3O4 high entropy oxides prepared via two different methods for the selective CH bond oxidation of p-chlorotoluene.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:36867932] [10.1016/j.jcis.2023.02.128]
4. Siyuan Chang, Sen Zhang, Tianyi Chen, Lei Xu, Sumin Ge, Bingfeng Li, Chenke Yun, Guoxin Zhang, Xuejun He, Xin Pan.  (2023)  Efficient synthesis of 5-hydroxymethyl-2-furancarboxylic acid from bio-based high-concentration 5-hydroxymethylfurfural via highly tolerant aldehyde dehydrogenase.  Molecular Catalysis,      [PMID:] [10.1016/j.mcat.2023.112966]
5. Xiaoqing Yuan, Ju Liu, Yanlei Wang, Xingming Jie, Jingyu Qin, Hongyan He.  (2022)  Ionic liquids enable highly efficient Knoevenagel reaction by dual-responsive emulsion microreactor.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.138941]
6. Meijiang Liu, Huifang Liu, Ning Li, Chaofeng Zhang, Jian Zhang, Feng Wang.  (2022)  Selective Oxidation of Glycerol into Formic Acid by Photogenerated Holes and Superoxide Radicals.  ChemSusChem,  15  (19): (e202201068).  [PMID:35916074] [10.1002/cssc.202201068]
7. Pengqi Zhu, Mengting Gao, Jin Zhang, Zhiwei Wu, Ruiyi Wang, Yunwei Wang, Eric R. Waclawik, Zhanfeng Zheng.  (2020)  Synergistic interaction between Ru and MgAl-LDH support for efficient hydrogen transfer reduction of carbonyl compounds under visible light.  APPLIED CATALYSIS B-ENVIRONMENTAL,      [PMID:] [10.1016/j.apcatb.2020.119640]
8. Zhu Anlian, Li Qixing, Feng Wanlu, Fan Dongshuang, Li Lingjun.  (2020)  Biocompatible Ionic Liquid Promote One-Pot Synthesis of 2-Amino-4H-Chromenes Under Ambient Conditions.  CATALYSIS LETTERS,  151  (3): (720-733).  [PMID:] [10.1007/s10562-020-03332-7]
9. Jiuli Han, Lu Bai, Shuangjiang Luo, Bingbing Yang, Yinge Bai, Shaojuan Zeng, Xiangping Zhang.  (2020)  Ionic liquid cobalt complex as O2 carrier in the PIM-1 membrane for O2/N2 separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2020.117041]
10. Dongdong Li, Luyao Wang, Ernesto Yagüe, Linlin Dai, Xiumei Zhao, Zibo Yang, Shuang Zhi, Yunhui Hu.  (2019)  Studies of proteasome inhibition and apoptosis induction in triple-negative breast cancer cells by novel amino acid–polypyridine–copper complex.  APPLIED ORGANOMETALLIC CHEMISTRY,  33  (10): (e5120).  [PMID:] [10.1002/aoc.5120]
11. Zhou Liu, Tiyun Yang, Yuxing Huang, Yang Liu, Liucheng Chen, Libo Deng, Ho Cheung Shum, Tiantian Kong.  (2019)  Electrocontrolled Liquid Marbles for Rapid Miniaturized Organic Reactions.  ADVANCED FUNCTIONAL MATERIALS,  29  (19): (1901101).  [PMID:] [10.1002/adfm.201901101]
12. Haohan Song, Junli Zhang, Xiao Wang, Yanmei Zhou, Chenggong Xu, Xiaobin Pang, Xiaojun Peng.  (2017)  A novel “turn-on” fluorescent probe with a large stokes shift for homocysteine and cysteine: Performance in living cells and zebrafish.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2017.12.010]
13. Yi Huang, Chunyan Wu, Wenwen Yuan, Yongmei Xia, Xiang Liu, Huamei Yang, Haijun Wang.  (2017)  Catalytic Aerobic Oxidation of Biomass-based Furfural into Maleic Acid in Aqueous Phase with Metalloporphyrin Catalysts.  JOURNAL OF THE CHINESE CHEMICAL SOCIETY,  64  (7): (786-794).  [PMID:] [10.1002/jccs.201700004]
14. Wang Qingming, Sun Huifang, Sha Weilin, Chen Juan, Gu Liuyue, Wang Dong, Tang Xinhui.  (2017)  An optical material for the detection of trace S2O3 2− in milk based on a copper complex.  BIOMETALS,  30  (3): (441-447).  [PMID:28405829] [10.1007/s10534-017-0017-y]
15. Xiang-Lan Wang, Yuan-Xia Li, Shuai-Liang Yang, Chen-Xi Zhang, Qing-Lun Wang.  (2017)  Two copper complexes based on nitronyl nitroxide with different halides: structures and magnetic properties.  JOURNAL OF COORDINATION CHEMISTRY,      [PMID:] [10.1080/00958972.2016.1271417]
16. Xiuquan Jia, Jiping Ma, Min Wang, Xiaofang Li, Jin Gao, Jie Xu.  (2016)  Alkali α-MnO2/NaxMnO2 collaboratively catalyzed ammoxidation–Pinner tandem reaction of aldehydes.  Catalysis Science & Technology,  (20): (7429-7436).  [PMID:] [10.1039/C6CY00874G]
17. Yufei Wu, Jie Hou, Yuliang Liu, Mingfu Zhang, Chen-Ho Tung, Yifeng Wang.  (2016)  Chemoselective Claisen–Schmidt bis-substitutional condensation catalyzed by an alkoxy-bridged dinuclear Ti(IV) cluster.  TETRAHEDRON,      [PMID:] [10.1016/j.tet.2016.01.055]
18. Yanghe Fu, Long Sun, Huan Yang, Lai Xu, Fumin Zhang, Weidong Zhu.  (2016)  Visible-light-induced aerobic photocatalytic oxidation of aromatic alcohols to aldehydes over Ni-doped NH2-MIL-125(Ti).  APPLIED CATALYSIS B-ENVIRONMENTAL,      [PMID:] [10.1016/j.apcatb.2016.01.038]
19. Yuanyuan Yue, Qiao Dong, Yajie Zhang, Xiaoge Li, Xuyang Yan, Yahui Sun, Jianming Liu.  (2015)  Synthesis of imidazole derivatives and the spectral characterization of the binding properties towards human serum albumin.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:26474241] [10.1016/j.saa.2015.09.023]
20. Song Wang, Pingwei Liu, Wen-Jun Wang, Zhiguo Zhang, Bo-Geng Li.  (2015)  Hyperbranched polyethylene-supported L-proline: a highly selective and recyclable organocatalyst for asymmetric aldol reactions.  Catalysis Science & Technology,  (7): (3798-3805).  [PMID:] [10.1039/C5CY00250H]
21. Yaqi Qin, Xueting Mu, Xiaoyu Feng, Kai Xu, Jinkang Ma, Lifeng Cao, Bing Teng.  (2025)  Design, synthesis and characterization of two new nonlinear optical crystals based on chalcone containing furan ring: FTB and FTC.  JOURNAL OF MOLECULAR STRUCTURE,      [PMID:] [10.1016/j.molstruc.2025.141720]
22. Yilin Wei, Zhiwei Sun, Qingqing Li, Dan Wu, Jianshe Wang, Yuexing Zhang, Chunbao Charles Xu, Renfeng Nie.  (2024)  Efficient reductive amination of furfural to furfurylamine promoted synergistically by surface Co0 and oxygen-vacant CoOx.  FUEL,      [PMID:] [10.1016/j.fuel.2024.131703]
23. Shandi Zhong, Cai Xu, Quanfu Long, Hang Zhou, Jianhai Yang, Jia Guo, Xiaozhong Wang, Liyan Dai.  (2024)  Highly catalytic performance for the selective C–H bond oxidation of p-chlorotoluene over Co, Cr co-doped OMS-2 catalyst.  CHEMICAL ENGINEERING SCIENCE,      [PMID:] [10.1016/j.ces.2024.120789]
24. Yong Song, Zhiyuan Jin, Jinsong Li, Wenjia Hao, Jiao Huang, Bo Jin, Rufang Peng.  (2024)  Low-Temperature Continuous Mechanochemical Synthesis of Hydantoin-Based Active Pharmaceutical Ingredients by Spiral Gas–Solid Two-Phase Flow.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.4c06480]
25. Kai Hu, Zhuo Wang, Hu Wang, Kanshe Li.  (2024)  Water-Soluble Supramolecular Polymer With Silver Ion Responsiveness.  JOURNAL OF APPLIED POLYMER SCIENCE,      [PMID:] [10.1002/app.56671]
26. Xueqin Yang, Yijing Shi, Guangguo Ying, Mengyuan Li, Zhili He, Longfei Shu.  (2024)  Cooperation among nitrifying microorganisms promotes the irreversible biotransformation of sulfamonomethoxine.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:38447730] [10.1016/j.scitotenv.2024.171395]
27. Zhen Zhang, Yiwen Wang, Pengbo Guo, Guilin Lu, Luchen Wu, Xinyu li.  (2024)  Designing MnO2@amorphous carbon core-shell structure as a cathode to enhance rate performance and cycling stability of aqueous zinc-ion batteries.  International Journal of Electrochemical Science,      [PMID:] [10.1016/j.ijoes.2024.100573]
28. Xuemei Tian, Suoqin Zhang, Liangyu Zheng.  (2015)  First Novozym 435 lipase-catalyzed Morita–Baylis–Hillman reaction in the presence of amides.  ENZYME AND MICROBIAL TECHNOLOGY,      [PMID:26827772] [10.1016/j.enzmictec.2015.12.006]
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.