≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 7 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Description
Phillyrin is a lignan found in the fruit ofForsythia suspensa.
| SMILES isoméricas | COC1=C(C=C(C=C1)[C@H]2[C@H]3CO[C@@H]([C@H]3CO2)C4=C(C=C(C=C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)OC)OC |
|---|---|
| PubChem CID | 24721571 |
| Peso molecular | 534.55 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Sensibilidade | Moisture sensitive |
|---|---|
| Peso molecular | 534.600 g/mol |
| XLogP3 | 0.800 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 8 |
| Exact Mass | 534.21 Da |
| Monoisotopic Mass | 534.21 Da |
| Topological Polar Surface Area | 146.000 Ų |
| Heavy Atom Count | 38 |
| Formal Charge | 0 |
| Complexity | 757.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Ying Ju, Chunling Yin, Yan Zhang, Xiangru Meng, Liuchuang Zhao, Leqian Hu. (2022) Rapid detection and quality evaluation of Shuang-Huang-Lian injection by ATR-IR and NIR spectroscopy combined with chemometrics. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:36283204] [10.1016/j.saa.2022.122008] |
| 2. Xin Guo, Pingping Cao, Xiongfeng Lian, Meng Hu, Jingyi Zhao, Wenjing Shen, Haili Wang, Hailong Yu, Yingzhu Chen. (2021) The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway. EUROPEAN JOURNAL OF PHARMACOLOGY, [PMID:34425100] [10.1016/j.ejphar.2021.174439] |
| 3. Duan Qiong, Li Ruochen, Wang Mingxiao, Cui Zhenting, Zhu Xia, Chen Fanghong, Han Feng, Ma Jianxin. (2024) Exploring the anti-NSCLC mechanism of phillyrin targeting inhibition of the HSP90-AKT pathway. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, [PMID:39356318] [10.1007/s00210-024-03481-1] |
| 4. Chenggang Huang, Jiajia Teng, Wei Liu, Junzhe Wang, An Liu. (2024) Modulation of macrophages by a phillyrin-loaded thermosensitive hydrogel promotes skin wound healing in mice. CYTOKINE, [PMID:38417214] [10.1016/j.cyto.2024.156556] |
| 5. Kaiping Xiang, Bing Wang, Lanying Wang, Yunfei Zhang, Hanzeng Li, Yanping Luo. (2024) Oxidative Stress, Oxidative Damage, and Cell Apoptosis: Toxicity Induced by Arecoline in Caenorhabditis elegans and Screening of Mitigating Agents. Toxins, 16 (8): (352). [PMID:39195762] [10.3390/toxins16080352] |
| 6. Zhirui Du, Xueqiao Yan, Lin Cheng, Haiyu Shen, Guoguo Zhi, Baojie Li, Qian Yu. (2025) Luteolin attenuates experimental dry eye disease via dual modulation of macrophage JAK-STAT signaling and corneal epithelial MAPK pathways. PHYTOMEDICINE, [PMID:41005053] [10.1016/j.phymed.2025.157300] |
| 7. Feng Li, Xinrong Fan, Bohao Wang, Jingyang Tong, Menglai Ling, Haibin Tong, Yumei Huang. (2025) Phillyrin counters β2 integrin-mediated neutrophil adhesion and chemotaxis to alleviate endotoxin-induced acute lung injury in neonatal rats. BIOCHEMICAL PHARMACOLOGY, [PMID:40210127] [10.1016/j.bcp.2025.116934] |
