Physcion - Moligand™, ≥98%(HPLC) , CAS No.521-61-9

CAS: 521-61-9 Cat. No.: P124619 Fórmula: C₁₆H₁₂O₅ Peso molecular: 284.26 Beilstein Registry Number: 6770499 Número CE: 208-315-7

GRAU & PUREZA Moligand™, ≥98%(HPLC)

Synonyms

1,8-dihydroxy-3-methoxy-6-methylanthracene-|Rheochrysidin - Physcione|Emodin monomethyl ether|8,9-dihydroxy-3-methyl-6-methoxy-1,10-anthraquinone|Parienin|1,8-Dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione|6-O-METHYLEMODIN|9,10-Anthracenedione, 1,8-dihydroxy-3-methoxy-6-methyl-|1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone|1,8-dihydroxy-3-methoxy-6-methyl-anthracene-9,10-dione|Rheochrysidin|Parietin;Rheochrysidin|fischione|Methoxyemodin|7-methoxy-2-methyl-4,5-dihydroxyanthracene-9,10-dione|9, 1,8-dihydroxy-3-methoxy-6-methyl-|Physcion|1,8-Dihydroxy-3-methoxy-6-methylanthraquinone, Emodin-3-methyl ether|EMODIN 3-METHYL ETHER [MI]|Physcione|PHYSCIONE-|CHRYSOPHANIC ACID, 6-METHOXY-|Emodin 3-methyl ether|Rheochrysidin (Physcione)|1,8-Dihydroxy-3-methyl-6-methoxy-9,10-anthraquinone|1,8-Dihydroxy-3-methoxy-6-methylanthra-9,10-quinone #|Emodin-3-methyl ether|1,8-dihydroxy-6-methoxy-3-methylanthraquinone|Physcion,(S)|SDCCGMLS-0066772.P001|Anthraquinone,8-dihydroxy-3-methoxy-6-methyl-|Parietin|1,8-Dihydroxy-3-methoxy-6-methylanthraquinone|1,8-Dihydroxy-3-methoxy-6-methyl-anthraquinone|8,9-dihydroxy-6-methyl-3-methoxy-1,10-anthraquinone

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Visão geral

Physcion is an anthraquinone derivative and is available as the active constituent of Chinese medicinal plants such as Rhubarb, Polygonum cuspidatum and Reynoutria multiflora. It exhibits various biological activities such as antitumor, antimicrobial, antifungal, antioxidant and antihuman cytomegalovirus activity.

Especificações

Sinónimos

1,8-dihydroxy-3-methoxy-6-methylanthracene- | Rheochrysidin - Physcione | Emodin monomethyl ether | 8,9-dihydroxy-3-methyl-6-methoxy-1,10-anthraquinone | Parienin | 1,8-Dihydroxy-3-methoxy-6-methyl-9,10-anthracenedione | 6-O-METHYLEMODIN | 9,10-Anthracenedione, 1,8-dihydroxy-3-methoxy-6-methyl- | 1,8-Dihydroxy-3-methyl-6-methoxyanthraquin Show more

Especificações e pureza

Moligand™, ≥98%(HPLC)

Mecanismos bioquímicos e fisiológicos

Anthraquinone-derivative found in medicinal herbs.Antifungal and antitumor anthraquinone

Condições de armazenamento de armazenamento

Store at 2-8°C,Argon charged

Enviado em

Wet ice

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%(HPLC)

Nomes e identificadores

Pubchem Sid

504751979

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504751979

Sorrisos canónicos

CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)OC

IUPAC Name

1,8-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione

InChIKey

FFWOKTFYGVYKIR-UHFFFAOYSA-N

INCHI

1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3

SMILES isoméricas

CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)OC

WGK Alemanha

3

RTECS

CB6720000

Peso molecular

284.26

Beilstein

6770499

Reaxy-Rn

1915778

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1915778&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Anthracenes
      • Subclass Anthraquinones

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Anthracenes
• Subclass: Anthraquinones
• Intermediate Tree Nodes: Not available
• Direct Parent: Anthraquinones
• Alternative Parents: Aryl ketones Anisoles Alkyl aryl ethers 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Vinylogous acids Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Anthraquinone - 9,10-anthraquinone - Aryl ketone - Anisole - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Vinylogous acid - Ketone - Ether - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aromatic homopolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as anthraquinones. These are organic compounds containing either anthracene-9,10-quinone, 1,4-anthraquinone, or 1,2-anthraquinone.
• External Descriptors: Anthraquinone type

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

MGAM Tclin Maltase-glucoamylase (654 Activities)

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VDR Tclin Vitamin D receptor (26531 Activities)

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P2RY12 Tclin Purinergic receptor P2Y12 (2369 Activities)

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ELANE Tclin Leukocyte elastase (8173 Activities)

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LCK Tclin Tyrosine-protein kinase LCK (9212 Activities)

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CTSG Tchem Cathepsin G (2304 Activities)

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GLA Tclin Alpha-galactosidase A (5444 Activities)

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

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EPHX2 Tchem Epoxide hydratase (3844 Activities)

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SI Tchem Sucrase-isomaltase (84 Activities)

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ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)

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A498 (42825 Activities)

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ACHN (49357 Activities)

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CAKI-1 (44928 Activities)

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CCRF-CEM (65223 Activities)

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COLO 205 (50209 Activities)

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DLD-1 (17511 Activities)

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HL-60 (67320 Activities)

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HT-29 (80576 Activities)

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K562 (73714 Activities)

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KM12 (47707 Activities)

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M14 (47487 Activities)

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MCF7 (126967 Activities)

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MOLT-4 (49676 Activities)

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OVCAR-3 (48710 Activities)

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OVCAR-4 (44535 Activities)

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OVCAR-5 (45555 Activities)

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OVCAR-8 (47708 Activities)

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PC-3 (62116 Activities)

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Raji (5516 Activities)

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RPMI-8226 (44974 Activities)

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RXF 631 (11415 Activities)

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SF-295 (48000 Activities)

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SK-MEL-2 (46422 Activities)

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SK-MEL-28 (48833 Activities)

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SK-MEL-5 (47095 Activities)

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SK-OV-3 (52876 Activities)

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SN12C (47755 Activities)

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SNB-19 (46794 Activities)

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SNB-78 (14240 Activities)

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U-251 (51189 Activities)

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UACC-257 (46019 Activities)

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UACC-62 (47335 Activities)

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UO-31 (46270 Activities)

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A549 (127892 Activities)

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EKVX (44102 Activities)

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A-431 (6446 Activities)

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NCI-H157 (619 Activities)

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NCI-H322M (45589 Activities)

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HCC 2998 (41480 Activities)

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Alvos associados (não humanos)

Alpha-chymotrypsin (819 Activities)

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Ttr Transthyretin (14 Activities)

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Papain (844 Activities)

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CELA2A Elastase 2A (403 Activities)

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Hdac6 Histone deacetylase 6 (222 Activities)

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protease Human rhinovirus A protease (1343 Activities)

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Streptococcus mutans (2687 Activities)

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Mycobacterium tuberculosis (203094 Activities)

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Phytophthora infestans (820 Activities)

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Entamoeba histolytica (2676 Activities)

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Fusarium oxysporum (3998 Activities)

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Hepatitis B virus (7925 Activities)

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Man1 Alpha-mannosidase (188 Activities)

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FUCA1 Alpha-L-fucosidase 1 (358 Activities)

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Txnrd2 Thioredoxin reductase 2, mitochondrial (18 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

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Erwinia amylovora (182 Activities)

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Spodoptera litura (1708 Activities)

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Mapt Microtubule-associated protein tau (6 Activities)

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ESR1 Estrogen receptor (4 Activities)

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Henosepilachna vigintioctopunctata (143 Activities)

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Fusarium graminearum (1554 Activities)

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Hordeum vulgare (329 Activities)

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Blumeria hordei (55 Activities)

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Mecanismos de ação

Propriedades químicas e físicas

• Peso molecular: 284.260 g/mol
• XLogP3: 3.000
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 284.068 Da
• Monoisotopic Mass: 284.068 Da
• Topological Polar Surface Area: 83.800 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 448.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at 2–8 °C under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 521-61-9, the molecular formula is C16H12O5, and the molecular weight is 284.26 g/mol. InChIKey FFWOKTFYGVYKIR-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.