PMBA - Moligand™ , Antagonist of glycine receptor α1 subunit;Antagonist of glycine receptor α2 subunit, CAS No.P612878, Antagonist of glycine receptor α1 subunit;Antagonist of glycine receptor α2 subunit

CAS: P612878 Cat. No.: P612878 PubChem CID: 4779
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
Synonyms
DTXSID201017650 | SDCCGSBI-0050981.P002 | LP01008 | EU-0101008 | NCGC00015789-02 | 2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid | NCGC00094301-02 | NCGC00094301-01 | SR-01000075469-1 | NCGC00261693-01 | CCG-205088 | GTPL4289 | Lopac0_0010
Storage
Room temperature
★
Size
USA
Alemanha (EU)*
Price
Qty
5mg
P612878-5mg
Sob encomenda · 8–12 semanas
799,90US$
25mg
P612878-25mg
Sob encomenda · 8–12 semanas
1714,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
DTXSID201017650 | SDCCGSBI-0050981.P002 | LP01008 | EU-0101008 | NCGC00015789-02 | 2-amino-3-[3-[2-(phosphonomethyl)phenyl]phenyl]propanoic acid | NCGC00094301-02 | NCGC00094301-01 | SR-01000075469-1 | NCGC00261693-01 | CCG-205088 | GTPL4289 | Lopac0_0010
Especificações e pureza
Moligand™
Condições de armazenamento de armazenamento
Room temperature
Grau
Moligand™
Tipo de ação
ANTAGONIST
Mecanismo de ação
Antagonist of glycine receptor α1 subunit;Antagonist of glycine receptor α2 subunit
Nomes e identificadores
Sorrisos canónicosOC(=O)C(Cc1cccc(c1)c1ccccc1CP(=O)(O)O)N
IUPAC Name2-amino-3-{3-[2-(phosphonomethyl)phenyl]phenyl}propanoic acid
InChIKeyNCEGJIHRQBRVJQ-UHFFFAOYSA-N
INCHI1S/C16H18NO5P/c17-15(16(18)19)9-11-4-3-6-12(8-11)14-7-2-1-5-13(14)10-23(20,21)22/h1-8,15H,9-10,17H2,(H,18,19)(H2,20,21,22)
SMILES isoméricas C1=CC=C(C(=C1)CP(=O)(O)O)C2=CC=CC(=C2)CC(C(=O)O)N
PubChem CID 4779

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClasseCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentPhenylalanine and derivatives
Alternative Parents Biphenyls and derivatives  Phenylpropanoic acids  Amphetamines and derivatives  Alpha amino acids  Aralkylamines  Organic phosphonic acids  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Organopnictogen compounds  Organophosphorus compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Phenylalanine or derivatives - Biphenyl - 3-phenylpropanoic-acid - Alpha-amino acid - Amphetamine or derivatives - Aralkylamine - Monocyclic benzene moiety - Benzenoid - Organophosphonic acid - Organophosphonic acid derivative - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Organophosphorus compound - Primary amine - Primary aliphatic amine - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organopnictogen compound - Organic oxygen compound - Amine - Aromatic homomonocyclic compound
DescriçãoThis compound belongs to the class of organic compounds known as phenylalanine and derivatives. These are compounds containing phenylalanine or a derivative thereof resulting from reaction of phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors Not available
Estrutura 3D
Modelo de Estrutura Química Interativa





Alvos associados (humanos)
GLRA2 Tchem Glycine receptor subunit alpha-2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GLRA1 Tclin Glycine receptor subunit alpha-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ARSA Tbio Cerebroside-sulfatase (655 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Alvos associados (não humanos)
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de ação
Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriedades químicas e físicas
Peso molecular335.290 g/mol
XLogP3-1.800
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass335.092 Da
Monoisotopic Mass335.092 Da
Topological Polar Surface Area121.000 Ų
Heavy Atom Count23
Formal Charge0
Complexity452.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
Referências
1. Kaili Wang, Yameng Zhu, Liuyingzi Yu, Lu Jiang, Xinya Chen, Zhihao Lu, Kun Gao, Xing Kang, Zhongyan Gong, Qiming Peng, Gang Lu.  (2024)  Modulating the Plasmon-Mediated Decarboxylation Reaction on Silver Nanoparticles by Changing the Surface Adsorption of Molecular Cocatalysts of p-Hydroxythiophenol.  Journal of Physical Chemistry C,      [PMID:] [10.1021/acs.jpcc.3c07887]
2. Yangyang Xu, Xian Zhang, Xiao-Song Zhu, Yi-Wei Shi.  (2024)  Silver-coated hollow fiber surface plasmon resonance sensor for glucose detection with enhanced limit of detection.  Nanoscale,  16  (14): (7085-7092).  [PMID:38488869] [10.1039/D4NR00421C]
3. Yangyang Xu, Xian Zhang, Xiao-Song Zhu, Yi-Wei Shi.  (2024)  Surface Plasmon Resonance-Based Highly Sensitive Hollow-Core Fiber Dopamine Sensor Using Dual-Recognition Strategy.  IEEE SENSORS JOURNAL,  24  (22): (36923-36929).  [PMID:] [10.1109/JSEN.2024.3473612]
Calculadoras de soluções
Revisões

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