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4 azide, 1 NHBoc (core), generation 2 for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Description
Polymer architecture: DendronGeneration: 2Core functional group: Boc-protected amineEnd group functionality: AzideNo. surface groups: 4Calculated mol. wt.: 1270.4 g/molBoc:tert-ButyloxycarbonylBis-MPA: 2,2-Bis(hydroxymethyl)propionic acid.Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. The azide-functionalized dendrimers can be readily functionalized using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC) or strain-promoted alkyne-azide cycloaddition (SPAAC). Additionally, the amine-functionalized core can be readily used in EDC or DCC coupling reactions (after boc deprotection) with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications.
Comprehensive hazard, handling, storage, and regulatory compliance document.
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