Pozelimab (anti-Complement C5) - Anticorpo primário, specific to C5, Human IgG4SP, INHIBITOR of Complement C5 inhibitor, INHIBITOR of Complement C5 inhibitor

CAS: 2096328-94-6 Cat. No.: Ab182838

GRADE & PURITY Animal Free, Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

Humano

Reactive species

Humano

Isotype

Human IgG4SP

Conjugation

Unconjugated

Visão geral

Pozelimab (anti-Complement C5) is a fully human IgG4 anti-C5 monoclonal antibody. Pozelimab (anti-Complement C5) binds to C5 and C5 variants with high affinity and blocks complement-mediated hemolysis. Pozelimab (anti-Complement C5) can be used for the research of complement-mediated diseases.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name

Pozelimab (anti-Complement C5) - Anticorpo primário, specific to C5, Human IgG4SP, INHIBITOR of Complement C5 inhibitor

Sinónimos

Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody | C5 antibody | C5a anaphylatoxin antibody | C5a antibody | C5b antibody | CO5_HUMAN antibody | Complement C5 alpha'' chain antibody | Complemen

Especificações e pureza

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Espécie hospedeira

Humano

Especificidade

C5

Conjugação

Unconjugated

Grau

Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated

Tipo de ação

INHIBITOR

Mecanismo de ação

INHIBITOR of Complement C5 inhibitor

Isótipo

Human IgG4SP

Tipo de corrente de luz

kappa

SDS-PAGE

144.78 kDa

Método de purificação

Protein A purified

Concentração

See COA

CAS

2096328-94-6

Armazenamento e envio

Forma

Liquid

Condições de armazenamento de armazenamento

Store at -80°C,Avoid repeated freezing and thawing

Enviado em

Dry ice packs + Cold packs

Estabilidade e armazenamento

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle

Imagens

ELISA: Pozelimab (anti-Complement C5) (Ab182838)

Pozelimab (anti-Complement C5) (Ab182838) - ELISA
Immobilized Recombinant Human Complement C5 protein at 2.0 μg/mL can bind Pozelimab (anti-Complement C5) (Ab182838) with the EC ₅₀  of 2.302 ng/mL.

SEC: Pozelimab (anti-Complement C5) (Ab182838)

Pozelimab (anti-Complement C5) (Ab182838) - SEC
The purity of Pozelimab (anti-Complement C5) (Ab182838) is more than 95% verified by HPLC.

Alvos associados (humanos)

C5 Tclin Complement C5 (0 Activities)

Discover Target: C5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de ação

Perguntas frequentes

What does Animal Free mean?

Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2096328-94-6.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Pozelimab (anti-Complement C5)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.