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· · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque RO-3 - Moligand™, ≥98%(HPLC) , Antagonist of P2X3, CAS No.1026582-88-6, Antagonist of P2X3
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
5-[[4,5-Dimetoxi-2-(metiletil)fenil]metil]-2,4-pirimidinadiamina | 5-(2-isopropil-4,5-dimetoxibenzil)pirimidina-2,4-diamina
Shipped In
Arca de gelo + almofadas de gelo
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Armazenar a -20°C Ships Arca de gelo + almofadas de gelo Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral O RO3 é um antagonista seletivo do recetor homomérico P2X3 e heteromérico P2X2/3
Specifications Sinónimos
5-[[4,5-Dimetoxi-2-(metiletil)fenil]metil]-2,4-pirimidinadiamina | 5-(2-isopropil-4,5-dimetoxibenzil)pirimidina-2,4-diamina
Especificações e pureza
Moligand™, ≥98%(HPLC)
Mecanismos bioquímicos e fisiológicos
Antagonista seletivo dos receptores homotípicos P2X3 e heterotípicos P2X2/3 (pIC50 7,0 e 5,9, respetivamente), inativo nos receptores P2X1, P2X2, P2X4, P2X5 e P2X7 (IC50 > 10 μM). Atenua a sensibilidade nociceptiva num modelo animal de dor
Condições de armazenamento de armazenamento
Armazenar a -20°C
Enviado em
Arca de gelo + almofadas de gelo
Mecanismo de ação
Antagonist of P2X3
Nomes e identificadores Pubchem Sid 504766254 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504766254 Sorrisos canónicos CC(C)C1=CC(=C(C=C1CC2=CN=C(N=C2N)N)OC)OC IUPAC Name 5-[(4,5-dimethoxy-2-propan-2-ylphenyl)methyl]pyrimidine-2,4-diamine InChIKey PYNPWUIBJMVRIG-UHFFFAOYSA-N INCHI 1S/C16H22N4O2/c1-9(2)12-7-14(22-4)13(21-3)6-10(12)5-11-8-19-16(18)20-15(11)17/h6-9H,5H2,1-4H3,(H4,17,18,19,20) SMILES isoméricas CC(C)C1=CC(=C(C=C1CC2=CN=C(N=C2N)N)OC)OC PubChem CID 11289644 Peso molecular 302.37
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Classe Benzene and substituted derivatives Subclass Methoxybenzenes Intermediate Tree Nodes Not available Direct Parent Dimethoxybenzenes Alternative Parents Phenylpropanes Cumenes Phenoxy compounds Anisoles Aminopyrimidines and derivatives Alkyl aryl ethers Imidolactams Heteroaromatic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Dimethoxybenzene - O-dimethoxybenzene - Cumene - Phenylpropane - Anisole - Phenoxy compound - Phenol ether - Aminopyrimidine - Alkyl aryl ether - Pyrimidine - Imidolactam - Heteroaromatic compound - Organoheterocyclic compound - Ether - Azacycle - Primary amine - Amine - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound Descrição This compound belongs to the class of organic compounds known as dimethoxybenzenes. These are organic aromatic compounds containing a monocyclic benzene moiety carrying exactly two methoxy groups. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Solubilidade Solvent:DMSO, Max Conc. mg/mL: 30.24, Max Conc. mM: 100 Peso molecular 302.370 g/mol XLogP3 2.000 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 5 Exact Mass 302.174 Da Monoisotopic Mass 302.174 Da Topological Polar Surface Area 96.300 Ų Heavy Atom Count 22 Formal Charge 0 Complexity 342.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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View Moligand™ grade guide →
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