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224,000+ produtos de pesquisa · Triple ISO certified · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque

Início
Por alvo / caminho / doença
Por vias de sinalização
Immunology/Inflammation
Receptor semelhante ao NOD (NLR)
Ruscogenin - Moligand™, 10mM in DMSO , CAS No.472-11-7

Ruscogenin - Moligand™, 10mM in DMSO , CAS No.472-11-7

Name: Ruscogenin - Moligand™, 10mM in DMSO , CAS No.472-11-7
SKU: R424112
Availability: InStock

CAS: 472-11-7 Cat. No.: R424112 Fórmula: C₂₇H₄₂O₄ Peso molecular: 430.62 Número CE: 207-447-2 PubChem CID: 441893

COA

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Ruscogenin - 10mM in DMSO CAS No(472-11-7) by Aladdin Scientific

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Disponível para encomenda

GRADE & PURITY Moligand™ ? 10mM in DMSO

Synonyms

Ruscogenin, >=98% (HPLC) | RUSCOGENIN [MART.] | EINECS 207-447-2 | Ruscogenin | S9183 | CCG-269015 | BXI92R2VUJ | C08909 | RUSCOGENIN [INCI] | Z2037319104 | (25R)-Spirost-5-ene-1beta,3beta-diol | Q27108184 | (25R)-SPIROST-5-ENE-1.BETA.,3.BETA.-DIOL | 5-Ch

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral Specifications Nomes e identificadores Documentation Advanced Data Estrutura 3D Alvos associados (humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Calculadoras de soluções Revisões

🧪

Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Product Describtion:

Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway and exerts significant anti-inflammatory and anti-thrombotic activities.

Specifications

Sinónimos

Especificações e pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Ruscogenin inhibits the expressions of TF, iNOS, and NF-kappaB p65 and is therefore a potential target for acute lung injury or sepsis.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Tipo de ação

INHIBITOR

Nomes e identificadores

Pubchem Sid	528775147
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/528775147
Sorrisos canónicos	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(C(CC(C6)O)O)C)C)C)OC1
IUPAC Name	(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,14R,16R)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-14,16-diol
InChIKey	QMQIQBOGXYYATH-IDABPMKMSA-N
INCHI	1S/C27H42O4/c1-15-7-10-27(30-14-15)16(2)24-22(31-27)13-21-19-6-5-17-11-18(28)12-23(29)26(17,4)20(19)8-9-25(21,24)3/h5,15-16,18-24,28-29H,6-14H2,1-4H3/t15-,16+,18-,19-,20+,21+,22+,23-,24+,25+,26+,27-/m1/s1
SMILES isoméricas	C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5([C@@H](C[C@@H](C6)O)O)C)C)C)OC1
PubChem CID	441893
Peso molecular	430.62

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estrutura 3D

Alvos associados (humanos)

BXPC-3 (2997 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THP-1 (11052 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Certificados（CoA,COO,BSE/TSE e Mapa de Análise)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Propriedades químicas e físicas

Peso molecular	430.600 g/mol
XLogP3	4.700
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	0
Exact Mass	430.308 Da
Monoisotopic Mass	430.308 Da
Topological Polar Surface Area	58.900 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	779.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	12
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Calculadoras de soluções

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Revisões

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