(S)-(+)-Ibuprofen - ≥98%(GC) , Cyclooxygenase inhibitor, CAS No.51146-56-6, Cyclooxygenase inhibitor
Em stock
SKU
S140886
Non-selective COX inhibitor
(S)-Ibuprofen is the active enantiomer of ibuprofen. (S)-Ibuprofen inhibits Cox-1 and Cox-2 with comparable potency (ID50 = 8.9-14 μM and 7.2-8.2 μM, respectively). (S)-Ibuprofen acts as a non-steroidal analgesic and antiinflammatory agent. This compound’s inhibition of Cox-1 and Cox-2 and activation of PPARα and PPARγ isoforms may be responsible for its pharmacological effects. (S)-(+)-Ibuprofen is the enantiomer associated with the anti-inflammatory action of ibuprofen, which is widely used as a nonsteroidal anti-inflammatory drug in racemic form.
Enantiomeric form of the anti-inflammatory agent ibuprofen used in pharmacokinetic studies.
Mais informação
| CAS | 51146-56-6 |
|---|---|
| Sinónimos | Dexibuprofenum | Dexibuprofenum [INN-Latin] | (+)-(S)-Ibuprofen | AB00513957 | Prestwick1_000907 | S-(+)-ibuprofen | S(+)-Ibuprofen | UNII-671DKG7P5S | (S)-2-(4-Isobutylphenyl)propanoic acid | (S)-2-(4-Isobutylphenyl)propionic acid | (S)-2-(4-isobutyl-phe |
| Especificações e pureza | ≥98%(GC) |
| Condições de armazenamento de armazenamento | Store at -20°C |
| Enviado em | Ice chest + Ice pads |
| Product Description | (S)-Ibuprofen is the active enantiomer of ibuprofen. (S)-Ibuprofen inhibits Cox-1 and Cox-2 with comparable potency (ID50 = 8.9-14 μM and 7.2-8.2 μM, respectively). (S)-Ibuprofen acts as a non-steroidal analgesic and antiinflammatory agent. This compound’s inhibition of Cox-1 and Cox-2 and activation of PPARα and PPARγ isoforms may be responsible for its pharmacological effects. (S)-(+)-Ibuprofen is the enantiomer associated with the anti-inflammatory action of ibuprofen, which is widely used as a nonsteroidal anti-inflammatory drug in racemic form. |
| Pubchem Sid | 504753594 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504753594 |
| Solubilidade | Soluble in DMSO (100 mM), ethanol (100 mM), dichloromethane, ethyl acetate, and methanol. Insoluble in water. |
| Número de identificação | MFCD00069289 |
| Número CE | 610-620-9 |
| PubChem CID | 39912 |
| Fórmula molecular | C13H18O2 |
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