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· · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque SAR131675 - ≥98% , CAS No.1433953-83-3
Disponível para encomenda
Synonyms
(R)-2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-ynyl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide | (R)-2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-yn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide
Shipped In
Arca de gelo + almofadas de gelo
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Armazenar a -20°C Ships Arca de gelo + almofadas de gelo Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
(R)-2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-ynyl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide | (R)-2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-yn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide
Especificações e pureza
≥98%
Mecanismos bioquímicos e fisiológicos
O VEGFR-3 é um recetor de tirosina quinase reconhecido pelo VEGF-C e pelo VEGF-D e desempenha um papel importante na linfangiogénese. Vários estudos clínicos e experimentais demonstraram que a linfangiogénese tumoral induzida pelo VEGFR-3
Condições de armazenamento de armazenamento
Armazenar a -20°C
Enviado em
Arca de gelo + almofadas de gelo
Nomes e identificadores Pubchem Sid 488202179 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488202179 Sorrisos canónicos CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#CC(C)(COC)O)C(=O)NC)N IUPAC Name 2-amino-1-ethyl-7-[(3R)-3-hydroxy-4-methoxy-3-methylbut-1-ynyl]-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide InChIKey PFMPOBVAYMTUOX-GOSISDBHSA-N INCHI 1S/C18H22N4O4/c1-5-22-15(19)13(17(24)20-3)14(23)12-7-6-11(21-16(12)22)8-9-18(2,25)10-26-4/h6-7,25H,5,10,19H2,1-4H3,(H,20,24)/t18-/m1/s1 SMILES isoméricas CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#C[C@](C)(COC)O)C(=O)NC)N PubChem CID 71295845 Peso molecular 358.39
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Classe Diazanaphthalenes Subclass Naphthyridines Intermediate Tree Nodes Not available Direct Parent Naphthyridines Alternative Parents Pyridinecarboxylic acids and derivatives Aminopyridines and derivatives Ynones Vinylogous amides Tertiary alcohols Heteroaromatic compounds Secondary carboxylic acid amides Amino acids and derivatives Dialkyl ethers Azacyclic compounds Primary amines Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Naphthyridine - Pyridine carboxylic acid or derivatives - Aminopyridine - Ynone - Pyridine - Heteroaromatic compound - Vinylogous amide - Tertiary alcohol - Amino acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Dialkyl ether - Ether - Azacycle - Hydrocarbon derivative - Organic nitrogen compound - Amine - Alcohol - Organic oxide - Organonitrogen compound - Organooxygen compound - Primary amine - Organic oxygen compound - Aromatic heteropolycyclic compound Descrição This compound belongs to the class of organic compounds known as naphthyridines. These are compounds containing a naphthyridine moiety, a naphthalene in which a carbon atom has been replaced by a nitrogen in each of the two rings. The naphthyridine skeleton can also be described as an assembly two fused pyridine rings, which do not share their nitrogen atom. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Solubilidade DMSO 30 mg/mL Water <1 mg/mL Ethanol <1 mg/mL Peso molecular 358.400 g/mol XLogP3 1.100 Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 6 Exact Mass 358.164 Da Monoisotopic Mass 358.164 Da Topological Polar Surface Area 118.000 Ų Heavy Atom Count 26 Formal Charge 0 Complexity 677.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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