SCH486757 - Moligand™, ≥98% , Nociceptin receptor agonist, CAS No.524019-25-8, Nociceptin receptor agonist

CAS: 524019-25-8 Cat. No.: S613491 Molecular Weight: 440.4 PubChem CID: 11597355
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
SCH-486757|SCH486757|524019-25-8|SCH 486757|8-Azabicyclo(3.2.1)octan-3-ol, 8-(bis(2-chlorophenyl)methyl)-3-(2-pyrimidinyl)-|2HV668N62T|(1R,5S)-8-[bis(2-chlorophenyl)methyl]-3-pyrimidin-2-yl-8-azabicyclo[3.2.1]octan-3-ol|UNII-2HV668N62T|GTPL8869|CHEMBL4297
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
S613491-1mg
1
$379.90
5mg
S613491-5mg
1
$799.90
10mg
S613491-10mg
1
$999.90
25mg
S613491-25mg
1
$1,443.90
50mg
S613491-50mg
1
$1,999.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

SCH-486757 is an agonist of nociceptin-1 (NOP1) and orphanin FQ peptide receptors and is used in the study of cough.

Specifications

Synonyms
SCH-486757 | SCH486757 | 524019-25-8 | SCH 486757 | 8-Azabicyclo(3.2.1)octan-3-ol, 8-(bis(2-chlorophenyl)methyl)-3-(2-pyrimidinyl)- | 2HV668N62T | (1R, 5S)-8-[bis(2-chlorophenyl)methyl]-3-pyrimidin-2-yl-8-azabicyclo[3.2.1]octan-3-ol | UNII-2HV668N62T | GTPL8869 | CHEMBL4297
Specifications & Purity
Moligand™, ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Nociceptin receptor agonist
Purity
≥98%
Product Properties
ALogP4.8
Names and Identifiers
Pubchem Sid528767072
Canonical SmilesClc1ccccc1C(c1ccccc1Cl)N1[C@@H]2CC[C@H]1CC(C2)(O)c1ncccn1
IUPAC Name(1R,5S)-8-[bis(2-chlorophenyl)methyl]-3-pyrimidin-2-yl-8-azabicyclo[3.2.1]octan-3-ol
InChIKeyMQWMHMZNBGQNMT-LDSCYUJKSA-N
INCHI1S/C24H23Cl2N3O/c25-20-8-3-1-6-18(20)22(19-7-2-4-9-21(19)26)29-16-10-11-17(29)15-24(30,14-16)23-27-12-5-13-28-23/h1-9,12-13,16-17,22,30H,10-11,14-15H2/t16-,17+,24?
Isomeric SMILES C1C[C@H]2CC(C[C@@H]1N2C(C3=CC=CC=C3Cl)C4=CC=CC=C4Cl)(C5=NC=CC=N5)O
PubChem CID 11597355
Molecular Weight 440.4

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
OPRL1 Tchem Nociceptin receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
K2408595Certificate of AnalysisSep 18, 2024 S613491
K2408596Certificate of AnalysisSep 18, 2024 S613491
K2408597Certificate of AnalysisSep 18, 2024 S613491
K2408598Certificate of AnalysisSep 18, 2024 S613491
K2408599Certificate of AnalysisSep 18, 2024 S613491
K2408600Certificate of AnalysisSep 18, 2024 S613491
K2408601Certificate of AnalysisSep 18, 2024 S613491
K2408602Certificate of AnalysisSep 18, 2024 S613491
K2408603Certificate of AnalysisSep 18, 2024 S613491
K2408604Certificate of AnalysisSep 18, 2024 S613491
Solution Calculators
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