SM-1295 - ≥98% , CAS No.1562375-46-5

CAS: 1562375-46-5 Cat. No.: S647225 Fórmula: C₂₉H₃₆BrN₅O₄ Peso molecular: 598.53

GRADE & PURITY ≥98%

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Visão geral

SM-1295 is an inhibitor of apoptosis protein (IAP) antagonist, with K d values of 3077 nM, 3.2 nM and 9.5 nM for XIAP-BIR3, c-IAP1-BIR3 and c-IAP2-BIR3, respectively

In Vitro

SM-1295 (compound 5) binds to both cIAP1 and cIAP2 proteins with K i values of <10 nM and displays a selectivity of >900-fold for cIAP1 over XIAP. SM-1295 (compound 5) exhibits an IC 50 of 46 nM in MDA-MB-231. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Kd: 3077 nM (XIAP-BIR3), 3.2 nM (c-IAP1-BIR3), 9.5 nM (c-IAP2-BIR3)

Specifications

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

SM-1295 is an inhibitor of apoptosis protein (IAP) antagonist, with K d values of 3077 nM, 3.2 nM and 9.5 nM for XIAP-BIR3, c-IAP1-BIR3 and c-IAP2-BIR3, respectively.

Condições de armazenamento de armazenamento

Store at -20°C,Desiccated

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥98%

Nomes e identificadores

Sorrisos canónicos

O=C([C@@H]1CC[C@@](CCN(C(CC2=CC=CC=C2)=O)C[C@@H]3NC([C@@H](NC)C)=O)([H])N1C3=O)NCC4=CC=C(Br)C=C4

Peso molecular

598.53

Propriedades químicas e físicas

• Solubilidade: DMSO : 310 mg/mL (517.94 mM; Need ultrasonic)

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1562375-46-5, the molecular formula is C29H36BrN5O4, and the molecular weight is 598.53 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.