ABCC1

Descrição	Multidrug resistance-associated protein 1

Gene and Protein Information

Gene ID	4363
Uniprot Accession IDs	P33527 A3RJX2 C9JPJ4 O14819 O43333 P78419 Q59GI9 Q9UQ97 Q9UQ99 Q9UQA0
Ensembl ID	ENSP00000382342
Symbol	MRP MRP1 MRP ABCC GS-X MRP1 ABC29
Family	Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Sequence	MALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Nome	Número de identificação fiscal	Other Gene ID	Sources
Chimp	453952	ABCC1	ATP binding cassette subfamily C member 1	9598	VGNC:51175	OMA, EggNOG
Macaque	717857	ABCC1	ATP binding cassette subfamily C member 1	9544		OMA, EggNOG
Mouse	17250	Abcc1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	10090	MGI:102676	Inparanoid, OMA, EggNOG
Rat	24565	Abcc1	ATP binding cassette subfamily C member 1	10116	RGD:3112	Inparanoid, OMA
Dog	403453	ABCC1	ATP binding cassette subfamily C member 1	9615	VGNC:54275	Inparanoid, OMA, EggNOG
Horse	791240	ABCC1	ATP binding cassette subfamily C member 1	9796	VGNC:14913	Inparanoid, OMA
Cow	281588	ABCC1	ATP binding cassette subfamily C member 1	9913	VGNC:25468	Inparanoid, OMA
Opossum	100023220	ABCC1	ATP binding cassette subfamily C member 1	13616		Inparanoid, OMA, EggNOG
Platypus		ABCC1	ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51]	9258		OMA, EggNOG
Chicken	395416	ABCC1	ATP binding cassette subfamily C member 1	9031	CGNC:49308	Inparanoid, OMA, EggNOG
Xenopus		abcc1	ATP binding cassette subfamily C member 1 [Source:Xenbase;Acc:XB-GENE-960171]	8364		OMA, EggNOG
S.cerevisiae	851713	YCF1	ATP-binding cassette glutathione S-conjugate transporter YCF1	4932	S000002542	OMA, EggNOG

Protein Classes

PANTHER Classes
protein / transporter / ATP-binding cassette (ABC) transporter / Multidrug resistance-associated protein 1

DTO Classes
protein / Transporter / ATP-binding cassette transporter family / ABCC subfamily / Multidrug resistance-associated protein 1

Associated Recombinant Proteins

Nome	Specification and purity	Expression system	Protein label	Disponibilidade	Ver Detalhes

Associated Antibodies

Nome	Specifications	Species reactivity	Aplicação	Disponibilidade	Ver Detalhes

Related active small molecules

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Nome	Direct Associated Targets	Disease Type	Mondoid

Bibliography