Potent and selective FAAH inhibitor
URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. Phase 1.
A cell permeable carbamate and potent inhibitor of fatty acid amide hydrolase (FAHH)
| CAS | 546141-08-6 |
|---|---|
| Sinónimos | CARBAMIC ACID, N-CYCLOHEXYL-, 3'-(AMINOCARBONYL)(1,1'-BIPHENYL)-3-YL ESTER | NCGC00165915-01 | 3'-(3-aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamat | 3-(3-aminocarbonyl)[1,1-biphenyl]-3-yl)-cyclohexylcarbamat | AS-18410 | Carbamic acid, N-cyclohex |
| Especificações e pureza | Moligand™, ≥98% |
| Condições de armazenamento de armazenamento | Store at -20°C |
| Enviado em | Ice chest + Ice pads |
| Product Description | URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. Phase 1. |
| Pubchem Sid | 528767595 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/528767595 |
| Solubilidade | Soluble in DMSO (~14 mg/ml), DMF (~10 mg/ml), 1:1 DMF:PBS(pH 7.2) (500 ug/ml), 1:2 DMSO:PBS(pH 7.2) (500 ug/ml), water (500 ug/ml) at 25 °C, and ethanol (5 mg/ml). |
| Número de identificação | MFCD05863934 |
| Número CE | 637-274-1 |
| PubChem CID | 1383884 |
