Veratrole - ≥99% , CAS No.91-16-7

CAS: 91-16-7 Cat. No.: V108547 Molecular Weight: 138.16 Beilstein Registry Number: 1364621 EC Number: 202-045-3 PubChem CID: 7043
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
Catechol dimethyl ether | EN300-16122 | HY-B1812 | 2-Dimethoxybenzol | Guaiacol methylether | NSC 16934 | Q-200062 | Q131994 | STL146732 | ghl.PD_Mitscher_leg0.397 | Methyl guaiacol | 1,2-Dimethoxybenzene, puriss., >=99.0% (GC) | AKOS000120951 | F1908-010
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25g
V108547-25g
2
$9.90
100g
V108547-100g
4
$19.90
500g
V108547-500g
3
$69.90
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 21 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Catechol dimethyl ether | EN300-16122 | HY-B1812 | 2-Dimethoxybenzol | Guaiacol methylether | NSC 16934 | Q-200062 | Q131994 | STL146732 | ghl.PD_Mitscher_leg0.397 | Methyl guaiacol | 1, 2-Dimethoxybenzene, puriss., >=99.0% (GC) | AKOS000120951 | F1908-010
Specifications & Purity
≥99%
Storage
Room temperature
Shipped In
Normal
Purity
≥99%
Names and Identifiers
Pubchem Sid504751232
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504751232
Canonical SmilesCOC1=CC=CC=C1OC
IUPAC Name1,2-dimethoxybenzene
InChIKeyABDKAPXRBAPSQN-UHFFFAOYSA-N
INCHI1S/C8H10O2/c1-9-7-5-3-4-6-8(7)10-2/h3-6H,1-2H3
Isomeric SMILES COC1=CC=CC=C1OC
WGK Germany 1
RTECS CZ6475000
PubChem CID 7043
Molecular Weight 138.16
Beilstein 1364621

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassMethoxybenzenes
Intermediate Tree Nodes Not available
Direct ParentDimethoxybenzenes
Alternative Parents Phenoxy compounds  Anisoles  Alkyl aryl ethers  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents O-dimethoxybenzene - Dimethoxybenzene - Phenoxy compound - Phenol ether - Anisole - Alkyl aryl ether - Ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as dimethoxybenzenes. These are organic aromatic compounds containing a monocyclic benzene moiety carrying exactly two methoxy groups.
External Descriptors dimethoxybenzene
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CA2 Tclin Carbonic anhydrase 2 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA6 Tclin Carbonic anhydrase VI (993 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA14 Tclin Carbonic anhydrase XIV (1305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Ca7 Carbonic anhydrase VII (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA4 Carbonic anhydrase IV (1713 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichoplusia ni (986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot NumberCertificate TypeDateItem
E2613555Certificate of AnalysisApr 27, 2026 V108547
E2613606Certificate of AnalysisApr 27, 2026 V108547
E2625654Certificate of AnalysisApr 27, 2026 V108547
K2110832Certificate of AnalysisAug 12, 2025 V108547
K2110729Certificate of AnalysisAug 12, 2025 V108547
K2110775Certificate of AnalysisAug 12, 2025 V108547
J2417333Certificate of AnalysisOct 24, 2024 V108547
I2509868Certificate of AnalysisJul 09, 2024 V108547
I2509869Certificate of AnalysisJul 09, 2024 V108547
G1919054Certificate of AnalysisMay 08, 2023 V108547
B2307243Certificate of AnalysisFeb 18, 2023 V108547
B2307231Certificate of AnalysisFeb 18, 2023 V108547
L2420094Certificate of AnalysisNov 17, 2021 V108547
K2111022Certificate of AnalysisNov 17, 2021 V108547
I2403033Certificate of AnalysisNov 17, 2021 V108547
E2516069Certificate of AnalysisNov 17, 2021 V108547
B2515056Certificate of AnalysisNov 17, 2021 V108547

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Chemical and Physical Properties
Freezing Point(°C)21 °C
Refractive Index1.5827
Flash Point(°F)87℃
Flash Point(°C)87℃
Boil Point(°C)206-207°C
Melt Point(°C)22-23°C
Molecular Weight138.160 g/mol
XLogP31.600
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass138.068 Da
Monoisotopic Mass138.068 Da
Topological Polar Surface Area18.500 Ų
Heavy Atom Count10
Formal Charge0
Complexity81.300
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Haoquan Guo, Xinyu Lu, Yue Yang, Jinhe Wei, Lizhi Wu, Li Tan, Yu Tang, Xiaoli Gu.  (2023)  Harvesting alkyl phenols from lignin monomers via selective hydrodeoxygenation under ambient pressure on Pd/α-MoC catalysts.  Molecular Catalysis,      [PMID:] [10.1016/j.mcat.2023.113041]
2. Lang Ming, Yuan-Wen Du, Ge-Ge Yuan, Qi Su, Xiao-Bing Shi, Huan Yu, Gong Chen.  (2023)  Spodoptera litura larvae are attracted by HvAV-3h-infected S. litura larvae-damaged pepper leaves.  PEST MANAGEMENT SCIENCE,  79  (8): (2713-2724).  [PMID:36905637] [10.1002/ps.7449]
3. Jiana Lin, Xiaoyan Ouyang, Yuling Hu, Gongke Li, Qisheng Zhong.  (2023)  Primary amide-functionalized cyclotricatechylene covalent organic frameworks membrane for efficient enrichment of melamine and its derivatives in migration solution of food contact materials.  JOURNAL OF SEPARATION SCIENCE,  46  (6): (202200862).  [PMID:36680331] [10.1002/jssc.202200862]
4. Yanan Qiao, Huifang Deng, Lihua Liu, Shuran Liu, Luyao Ren, Chuandao Shi, Xi Chen, Lixia Guan, Weiran Liu, Zehua Li, Yunlan Li.  (2023)  Highly Accessible Computational Prediction and In Vivo/In Vitro Experimental Validation: Novel Synthetic Phenyl Ketone Derivatives as Promising Agents against NAFLD via Modulating Oxidoreductase Activity.  Oxidative Medicine and Cellular Longevity,      [PMID:36659905] [10.1155/2023/3782230]
5. Xinxiu Cao, Liang Xie, Xinyu Zhu, Jiayu Lv, Hui Fan.  (2022)  The principles of selecting green solvent additives for optimizing the phase separation structure of polymer solar cells based on PTB7:PC71BM.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2022.111603]
6. Yang Guangxu, Gong Zhenggang, Luo Xiaolin, Shuai Li.  (2022)  Revisiting alkaline cupric oxide oxidation method for lignin structural analysis.  Frontiers in Bioengineering and Biotechnology,      [PMID:36159682] [10.3389/fbioe.2022.1002145]
7. Xiaoyan Ouyang, Ruiyu Liang, Yuling Hu, Gongke Li, Changying Hu, Qisheng Zhong.  (2021)  Hollow tube covalent organic framework for syringe filter-based extraction of ultraviolet stabilizer in food contact materials.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:34537658] [10.1016/j.chroma.2021.462538]
8. Zhenyu Lu, Xiaotian Lu, Ling Xia, Yanhui Zhong, Gongke Li, Yufei Hu.  (2021)  Cobalt doped nitrogenous porous carbon derived from covalent organic framework as cataluminescence catalyst for rapid determination of n-hexane in edible oil.  TALANTA,      [PMID:34074414] [10.1016/j.talanta.2021.122428]
9. Haichuan Zhang, Yang Liu, Shiyu Fu, Yulin Deng.  (2020)  Selective hydrodeoxygenation of lignin model compound (3,4-dimethoxybenzyl alcohol) by Pd/CNX catalyst.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:33345971] [10.1016/j.ijbiomac.2020.12.092]
10. Lei Zhang, Gan Jin, Tianlin Ma, Shi Wang.  (2020)  Ion transport in topological all-solid-state polymer electrolyte improved via graphene-oxide.  JOURNAL OF APPLIED POLYMER SCIENCE,  138  (14): (50173).  [PMID:] [10.1002/app.50173]
11. Jindong Wang, Wenzhi Li, Huizhen Wang, Ajibola Temitope Ogunbiyi, Xiaomeng Dou, Qiaozhi Ma.  (2020)  Effects of the novel catalyst Ni–S2O82−–K2O/TiO2 on efficient lignin depolymerization.  RSC Advances,  10  (14): (8558-8567).  [PMID:35497830] [10.1039/C9RA10675H]
12. Ruiyu Liang, Yuling Hu, Gongke Li.  (2020)  Photochemical synthesis of magnetic covalent organic framework/carbon nanotube composite and its enrichment of heterocyclic aromatic amines in food samples.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:31959461] [10.1016/j.chroma.2020.460867]
13. Cheng Hao, Wu Shubin, Huang Jinbao, Zhang Xiaohua.  (2017)  Direct evidence from in situ FTIR spectroscopy that o-quinonemethide is a key intermediate during the pyrolysis of guaiacol.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  409  (10): (2531-2537).  [PMID:28188351] [10.1007/s00216-017-0194-0]
14. Xiaohua Li, Zhitao Lei, Yu Cao, Shanshan Shao, Shiliang Wu.  (2025)  Aqueous-phase hydrogenation of various lignin-derived phenols to cycloketones as platform compounds over Br modified metal-acid mixed catalyst.  ENERGY,      [PMID:] [10.1016/j.energy.2025.135025]
15. Hairui Jiao, Guifeng Xu, Yushuai Sang, Hong Chen, Yongdan Li.  (2024)  Direct conversion of enzymatic hydrolysis lignin to cycloalkane fuel with hydrotalcite-derived Ni catalyst.  CATALYSIS TODAY,      [PMID:] [10.1016/j.cattod.2024.114542]
16. Haoquan Guo, Jiwu Zhao, Yu Chen, Xinyu Lu, Yue Yang, Chenrong Ding, Lizhi Wu, Li Tan, Jinlin Long, Guohui Yang, Yu Tang, Noritatsu Tsubaki, Xiaoli Gu.  (2024)  Mechanistic Insights into Hydrodeoxygenation of Lignin Derivatives over Ni Single Atoms Supported on Mo2C.  ACS Catalysis,      [PMID:] [10.1021/acscatal.3c04555]
17. Zifan Wu, Lu Chen, Yacong Deng, Yuting Qiu, Bin Liu, Yichuan Li, Yuan Pan, Bin Dong, Yongming Chai.  (2025)  Direct solvolysis of papermaking black liquor in strong alkali coupled with catalytic hydrodeoxygenation to produce aviation fuel-range arenes.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2025.121823]
18. Shao-Lu Li, Qiyu Duan, Mengfan Wang, Bo Wu, Ning Yu, Genghao Gong, Yunxia Hu.  (2025)  High-performance microporous organic solvent nanofiltration composite membrane prepared from a contorted maleimidoanthracene biscatechol monomer.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.162706]
19. Zifan Wu, Lu Chen, Yacong Deng, Fengyu Tian, Guangzheng Sun, Yuting Qiu, Yichuan Li, Yuan Pan, Bin Liu, Bin Dong, Yongming Chai.  (2025)  Ni-Mo alloy anchored on carbon nitride coated γ-Al2O3 for hydrodeoxygenation of lignin-derived phenols into aviation fuel-range cycloalkanes.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.164876]
20. Nian Cao, Yubo Yang, Xiaoling Xiong, Bohan Zhang, Ping Xiang, Fan Yang.  (2026)  Dynamic sensory mapping: how sip volume shapes sensory perception and drinking comfort of Jiangxiangxing Baijiu.  INTERNATIONAL JOURNAL OF FOOD PROPERTIES,      [PMID:] [10.1080/10942912.2026.2618833]
21. Xin Han, Shanguang Xu, Fan Zhang, Ruiying Chai, Shanguo Du, Xiuling Jiao, Dairong Chen, Jie Zhang.  (2026)  Enhanced Hydrodeoxygenation of Guaiacol to Phenol over MgO-Supported Pt Catalysts: The Critical Role of Sodium Promotion.  ACS Catalysis,      [PMID:] [10.1021/acscatal.6c00446]
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