1,6-Dihydroxynaphthalene - ≥99%(GC) , CAS No.575-44-0

CAS: 575-44-0 Cat. No.: D154708 Molecular Weight: 160.17 Beilstein Registry Number: 6(3)5279 EC Number: 209-386-7

GRADE & PURITY ≥99%(GC)

Synonyms

BDBM36288 | CI 76630 | 1,6-DIHYDROXY NAPHTHALENE | 34C30KW024 | 1,6-naphthalene diol | 6-Hydroxy-1-naphthol | NSC 7201 | PD005577 | AKOS000496309 | FT-0607003 | C.I. 76630 | F11438 | EN300-105164 | 2,5-Naphthalenediol | FS-3180 | Q27096881 | UNII-34C30KW0

Storage

Room temperature,Argon charged,Desiccated,Cool

Shipped In

Normal

Specifications

Synonyms

BDBM36288 | CI 76630 | 1, 6-DIHYDROXY NAPHTHALENE | 34C30KW024 | 1, 6-naphthalene diol | 6-Hydroxy-1-naphthol | NSC 7201 | PD005577 | AKOS000496309 | FT-0607003 | C.I. 76630 | F11438 | EN300-105164 | 2, 5-Naphthalenediol | FS-3180 | Q27096881 | UNII-34C30KW0

Specifications & Purity

≥99%(GC)

Storage

Room temperature, Argon charged, Desiccated, Cool

Shipped In

Normal

Purity

≥99%(GC)

Names and Identifiers

• Pubchem Sid: 488184147
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488184147
• Canonical Smiles: C1=CC2=C(C=CC(=C2)O)C(=C1)O
• IUPAC Name: naphthalene-1,6-diol
• InChIKey: FZZQNEVOYIYFPF-UHFFFAOYSA-N
• INCHI: 1S/C10H8O2/c11-8-4-5-9-7(6-8)2-1-3-10(9)12/h1-6,11-12H
• Isomeric SMILES: C1=CC2=C(C=CC(=C2)O)C(=C1)O
• Molecular Weight: 160.17
• Beilstein: 6(3)5279
• Reaxy-Rn: 1939032
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1939032&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Naphthalenes
      • Subclass Naphthols and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Naphthalenes
• Subclass: Naphthols and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Naphthols and derivatives
• Alternative Parents: 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Organooxygen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: 1-naphthol - 2-naphthol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homopolycyclic compound
• Description: This compound belongs to the class of organic compounds known as naphthols and derivatives. These are naphthalene derivatives carrying one or more hydroxyl (-OH) groups at any ring position.
• External Descriptors: naphthalenediol

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

T-24 (2342 Activities)

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IDO1 Tchem Indoleamine 2,3-dioxygenase (6650 Activities)

Discover Target: IDO1

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HFL1 (586 Activities)

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Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Air sensitive
• Melt Point(°C): 135 °C
• Molecular Weight: 160.170 g/mol
• XLogP3: 1.900
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 160.052 Da
• Monoisotopic Mass: 160.052 Da
• Topological Polar Surface Area: 40.500 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 158.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Minjie Peng, Yufeng Sun, Wen Zang, Changyong Gao, Lijing Miao, Aiguo Wu, Yujie Zhang.  (2023)  A highly sensitive method for the detection of p-Aminophenol based on Cu–Au nanoparticles and KIO3.  ANALYTICA CHIMICA ACTA,      [PMID:37977800] [10.1016/j.aca.2023.341954]

2. Anhua Wei, Jingfang OuYang, Yuyang Guo, Suju Jiang, Feifei Chen, Jun Huang, Qi Xiao, Zihua Wu.  (2023)  Controlled synthesis of monodisperse gold nanorods with a small diameter of around 10 nm and largest plasmon wavelength of 1200 nm.  PHYSICAL CHEMISTRY CHEMICAL PHYSICS,  25  (31): (20843-20853).  [PMID:37503681] [10.1039/D3CP02203J]

3. Xiao Yang, Yi Zhao, Qiuju Xu, Xiangcheng Yuan, Jinzhang Liu.  (2022)  Unraveling Factors Affecting Performance of Quinone-based Polymer Cathode in Aqueous Zinc-Ion Battery.  Batteries & Supercaps,  6  (3): (e202200480).  [PMID:] [10.1002/batt.202200480]

4. Yuan Zu, Lishuai Zong, Jinyan Wang, Xigao Jian.  (2021)  Kinetic analysis of the curing of branched phthalonitrile resin based on dynamic differential scanning calorimetry.  POLYMER TESTING,      [PMID:] [10.1016/j.polymertesting.2021.107062]

5. Shiwei Zhang, Jiurong Li, Xiao Gong.  (2024)  A Strategy for Rapid Synthesis of Carbon Nanodots with Reversible Photoluminescence Switching for Sensitive Dynamic Anti-Counterfeiting.  Advanced Optical Materials,  12  (22): (2400648).  [PMID:] [10.1002/adom.202400648]

6. Xingzhong Chen, Fang Yan, Jiurong Li, Xiao Gong.  (2025)  Control Synthesis of Multicolor Emitting Carbonized Polymer Dots Using Different Dihydroxynaphthalene Isomers.  JACS Au,      [PMID:40151271] [10.1021/jacsau.4c01220]

7. Shimin Geng, Yongtao Hu, Xinwen Hong, Tingting Chen, Mingen Fei, Shuyi Wu, Renhui Qiu, Wendi Liu.  (2025)  Palm oil-based waterborne polyurethanes: Achieving high-solid and low-viscosity through bimodal particle design.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.165490]