Epigenética - Aurora quinasa Supplier | High Purity

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ZM-447439, Inhibitor of aurora kinase A;Inhibitor of aurora kinase B
CAS: 331771-20-1 PubChem CID: 9914412 Fórmula: C₂₉H₃₁N₅O₄ Peso molecular: 513.59

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: Z125121
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Nombre IUPAC

N-[4-[[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenyl]benzamide

SMILES

COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5

InChIKey
OGNYUTNQZVRGMN-UHFFFAOYSA-N

InChI

1S/C29H31N5O4/c1-36-26-18-24-25(19-27(26)38-15-5-12-34-13-16-37-17-14-34)30-20-31-28(24)32-22-8-10-23(11-9-22)33-29(35)21-6-3-2-4-7-21/h2-4,6-11,18-20show more

Sinónimos
(S)-1-(Benzyloxy)-2,3-epoxypropane | N-[4-[[6-Methoxy-7-[3-(4-morpholiny l)propoxy]-4-quinazolinyl]amino]phenyl]benza...
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MK-8745
CAS: 885325-71-3 Fórmula: C₂₀H₁₉ClFN₅OS Peso molecular: 431.91

≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: M333437
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Nombre IUPAC

(3-chloro-2-fluorophenyl)-[4-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]piperazin-1-yl]methanone

SMILES

C1CN(CCN1CC2=NC(=CC=C2)NC3=NC=CS3)C(=O)C4=C(C(=CC=C4)Cl)F

InChIKey
YCRFPWKUUNKNDN-UHFFFAOYSA-N

InChI

1S/C20H19ClFN5OS/c21-16-5-2-4-15(18(16)22)19(28)27-10-8-26(9-11-27)13-14-3-1-6-17(24-14)25-20-23-7-12-29-20/h1-7,12H,8-11,13H2,(H,23,24,25)

Sinónimos
(3-Chloro-2-fluorophenyl)[4-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-1-piperazinyl]-methanone | 1-(3-Chloro-2-fluor...
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SNS-314 Mesylate
CAS: 1146618-41-8 PubChem CID: 24995523 Fórmula: C₁₈H₁₅ClN₆OS₂.CH₄O₃S Peso molecular: 527.04

≥98%

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Nombre IUPAC

1-(3-chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea;methanesulfonic acid

SMILES

CS(=O)(=O)O.C1=CC(=CC(=C1)Cl)NC(=O)NC2=NC=C(S2)CCNC3=NC=NC4=C3SC=C4

InChIKey
FYCODPVDEFFWSR-UHFFFAOYSA-N

InChI

1S/C18H15ClN6OS2.CH4O3S/c19-11-2-1-3-12(8-11)24-17(26)25-18-21-9-13(28-18)4-6-20-16-15-14(5-7-27-15)22-10-23-16;1-5(2,3)4/h1-3,5,7-10H,4,6H2,(H,20,22,show more

Sinónimos
BCP24792 | HMS3654A12 | MLS006011040 | SCHEMBL17257952 | N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamin...
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Hesperadin, Inhibitor of aurora kinase B
CAS: 422513-13-1 Fórmula: C₂₉H₃₂N₄O₃S Peso molecular: 516.67

Moligand™ ? ≥98%

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Nombre IUPAC

N-[2-hydroxy-3-[C-phenyl-N-[4-(piperidin-1-ylmethyl)phenyl]carbonimidoyl]-1H-indol-5-yl]ethanesulfonamide

SMILES

CCS(=O)(=O)NC1=CC2=C(C=C1)NC(=C2C(=NC3=CC=C(C=C3)CN4CCCCC4)C5=CC=CC=C5)O

InChIKey
HYHIYZMIFPJROG-UHFFFAOYSA-N

InChI

1S/C29H32N4O3S/c1-2-37(35,36)32-24-15-16-26-25(19-24)27(29(34)31-26)28(22-9-5-3-6-10-22)30-23-13-11-21(12-14-23)20-33-17-7-4-8-18-33/h3,5-6,9-16,19,31show more

Sinónimos
BDBM192753 | N-[(3Z)-2-oxo-3-[phenyl-[4-(piperidin-1-ylmethyl)anilino]methylidene]-1H-indol-5-yl]ethanesulfonamide | ...
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PF-477736, Inhibitor of checkpoint kinase 1;Inhibitor of checkpoint kinase 2
CAS: 952021-60-2 Fórmula: C₂₂H₂₅N₇O₂ Peso molecular: 419.48

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: P120184
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Nombre IUPAC

(2R)-2-amino-2-cyclohexyl-N-[2-(1-methylpyrazol-4-yl)-9-oxo-3,10,11-triazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13),11-pentaen-6-yl]acetamide

SMILES

CN1C=C(C=N1)C2=C3C=NNC(=O)C4=C3C(=CC(=C4)NC(=O)C(C5CCCCC5)N)N2

InChIKey
NDEXUOWTGYUVGA-LJQANCHMSA-N

InChI

1S/C22H25N7O2/c1-29-11-13(9-25-29)20-16-10-24-28-21(30)15-7-14(8-17(27-20)18(15)16)26-22(31)19(23)12-5-3-2-4-6-12/h7-12,19,27H,2-6,23H2,1H3,(H,26,31)(show more

Sinónimos
(2R)-2-amino-2-cyclohexyl-N-[2-(1-methyl-1H-pyrazol-4-yl)-9-oxo-3,10,11-triazatricyclo[6.4.1.0,4,13]trideca-1,4(13),5...
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KW-2449, Tyrosine-protein kinase ABL inhibitor
CAS: 1000669-72-6 Fórmula: C₂₀H₂₀N₄O Peso molecular: 332.4

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: K127169
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Nombre IUPAC

[4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone

SMILES

C1CN(CCN1)C(=O)C2=CC=C(C=C2)C=CC3=NNC4=CC=CC=C43

InChIKey
YYLKKYCXAOBSRM-JXMROGBWSA-N

InChI

1S/C20H20N4O/c25-20(24-13-11-21-12-14-24)16-8-5-15(6-9-16)7-10-19-17-3-1-2-4-18(17)22-23-19/h1-10,21H,11-14H2,(H,22,23)/b10-7+

Sinónimos
(E)-1-{4-[2-(1H-indazol-3-yl)vinyl]benzoyl}piperazine | NCGC00346569-07 | (E)-(4-(2-(1H-Indazol-3-yl)vinyl)-phenyl)(p...
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NU 6140, Inhibitor of aurora kinase A;Inhibitor of aurora kinase B;Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 5;Inhibitor of cyclin dependent kinase 7;In
CAS: 444723-13-1 Fórmula: C₂₃H₃₀N₆O₂ Peso molecular: 422.52

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: N275662
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Nombre IUPAC

4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]-N,N-diethylbenzamide

SMILES

CCN(CC)C(=O)C1=CC=C(C=C1)NC2=NC3=C(C(=N2)OCC4CCCCC4)NC=N3

InChIKey
XHEQSRJCJTWWAH-UHFFFAOYSA-N

InChI

1S/C23H30N6O2/c1-3-29(4-2)22(30)17-10-12-18(13-11-17)26-23-27-20-19(24-15-25-20)21(28-23)31-14-16-8-6-5-7-9-16/h10-13,15-16H,3-9,14H2,1-2H3,(H2,24,25,show more

Sinónimos
4-{[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino}-N,N-diethylbenzamide | E73484 | SCHEMBL2169233 | NU6140, >=98% (HPLC) ...
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PF-03814735
CAS: 942487-16-3 Fórmula: C₂₃H₂₅F₃N₆O₂ Peso molecular: 474.48

≥98%

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: P127543
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Nombre IUPAC

N-[2-[(1R,8S)-4-[[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-11-azatricyclo[6.2.1.02,7]undeca-2(7),3,5-trien-11-yl]-2-oxoethyl]acetashow more

SMILES

CC(=O)NCC(=O)N1C2CCC1C3=C2C=CC(=C3)NC4=NC=C(C(=N4)NC5CCC5)C(F)(F)F

InChIKey
RYYNGWLOYLRZLK-RBUKOAKNSA-N

InChI

1S/C23H25F3N6O2/c1-12(33)27-11-20(34)32-18-7-8-19(32)16-9-14(5-6-15(16)18)30-22-28-10-17(23(24,25)26)21(31-22)29-13-3-2-4-13/h5-6,9-10,13,18-19H,2-4,7show more

Sinónimos
UNII-6V5T4O5758 | NSC801015 | NSC-801015 | DTXSID601025621 | C23H25F3N6O2 | Q27265567 | PF03814735 | PF-03814735 | s2...
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MK-5108 (VX-689), Serine/threonine-protein kinase Aurora-A inhibitor
CAS: 1010085-13-8 Fórmula: C₂₂H₂₁ClFN₃O₃S Peso molecular: 461.94

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: M127979
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Nombre IUPAC

4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid

SMILES

C1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O

InChIKey
LCVIRAZGMYMNNT-UHFFFAOYSA-N

InChI

1S/C22H21ClFN3O3S/c23-16-4-2-5-17(19(16)24)30-15-7-9-22(10-8-15,20(28)29)13-14-3-1-6-18(26-14)27-21-25-11-12-31-21/h1-6,11-12,15H,7-10,13H2,(H,28,29)(show more

Sinónimos
HMS3656D06 | NCGC00024591-03 | BRD-K53665955-001-01-4 | GTPL8061 | MK 5108 | NSC800796 | NSC-800796 | MFCD22124479 | ...
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Palmatine
CAS: 3486-67-7 Fórmula: C₂₁H₂₂NO₄+ Peso molecular: 352.4

≥97%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: P111384
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Nombre IUPAC

2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium

SMILES

COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC

InChIKey
QUCQEUCGKKTEBI-UHFFFAOYSA-N

InChI

1S/C21H22NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,9-12H,7-8H2,1-4H3/q+1

Sinónimos
KBio2_007496 | PALMITINE | 7,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxyberbinium | KBio1_001659 | KBio3_001854 | Palma...
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AZD1152, Serine/threonine-protein kinase Aurora-B inhibitor
CAS: 722543-31-9 Fórmula: C₂₆H₃₁FN₇O₆P Peso molecular: 587.54

Moligand™ ? ≥98%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: A126951
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Nombre IUPAC

2-[ethyl-[3-[4-[[5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl]amino]quinazolin-7-yl]oxypropyl]amino]ethyl dihydrogen phosphate

SMILES

CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCOP(=O)(O)O

InChIKey
GBJVVSCPOBPEIT-UHFFFAOYSA-N

InChI

1S/C26H31FN7O6P/c1-2-34(10-12-40-41(36,37)38)9-4-11-39-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(35)30-19-6-3-5-18(27)13-19/h3,5-8,show more

Sinónimos
2-[ethyl-[3-[4-[[5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl]amino]quinazolin-7-yl]oxypropyl]amino]ethyl dihyd...
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Palmatine
CAS: 3486-67-7 Fórmula: C₂₁H₂₂NO₄+ Peso molecular: 352.4

Analytical standard ? Moligand™ ? ≥97%

● En stock — Almacén en EE. UU., envío a la EU* Articulo #: P111383
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Nombre IUPAC

2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium

SMILES

COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC

InChIKey
QUCQEUCGKKTEBI-UHFFFAOYSA-N

InChI

1S/C21H22NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,9-12H,7-8H2,1-4H3/q+1

Sinónimos
KBio2_007496 | PALMITINE | 7,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxyberbinium | KBio1_001659 | KBio3_001854 | Palma...

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Preguntas frecuentes

Which compounds are listed for Aurora Kinase?

Compounds associated with Aurora Kinase are grouped here under the Epigenetics classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.

How does Aurora Kinase sit within Epigenetics?

Aurora Kinase is one target listing within the Epigenetics classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.

What data should I check before ordering a compound from Aurora Kinase?

For compounds listed under Aurora Kinase, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

How do I find related targets or backup compounds for Aurora Kinase?

Browse the parent Epigenetics listing to reach targets neighbouring Aurora Kinase, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.