Determine the necessary mass, volume, or concentration for preparing a solution.
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≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 34 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
2-Acetylpyridine can be used in the synthesis of:
• A near-infrared fluorescent probe for monitoring pH changes in living cells.
• Biologically active ligands for preparing various metal complexes including Co(II), Ni(II), Cu(II) and Zn(II).
• A water-soluble, time-gated luminescence probe for singlet oxygen detection.
• 2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents.
| Pubchem Sid | 488181965 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488181965 |
| Canonical Smiles | CC(=O)C1=CC=CC=N1 |
| IUPAC Name | 1-pyridin-2-ylethanone |
| InChIKey | AJKVQEKCUACUMD-UHFFFAOYSA-N |
| INCHI | 1S/C7H7NO/c1-6(9)7-4-2-3-5-8-7/h2-5H,1H3 |
| Isomeric SMILES | CC(=O)C1=CC=CC=N1 |
| WGK Germany | 3 |
| Molecular Weight | 121.14 |
| Beilstein | 107759 |
| Reaxy-Rn | 107759 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=107759&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic oxygen compounds |
| Class | Organooxygen compounds |
| Subclass | Carbonyl compounds |
| Intermediate Tree Nodes | Ketones - Aryl ketones |
| Direct Parent | Aryl alkyl ketones |
| Alternative Parents | Pyridines and derivatives Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Aryl alkyl ketone - Pyridine - Heteroaromatic compound - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as aryl alkyl ketones. These are ketones have the generic structure RC(=O)R', where R = aryl group and R'=alkyl group. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 08, 2026 | A106232 | |
| Certificate of Analysis | May 12, 2025 | A106232 | |
| Certificate of Analysis | May 12, 2025 | A106232 | |
| Certificate of Analysis | May 12, 2025 | A106232 | |
| Certificate of Analysis | Mar 20, 2024 | A106232 | |
| Certificate of Analysis | Mar 20, 2024 | A106232 | |
| Certificate of Analysis | Mar 20, 2024 | A106232 | |
| Certificate of Analysis | Mar 20, 2024 | A106232 | |
| Certificate of Analysis | Mar 20, 2024 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Mar 27, 2022 | A106232 | |
| Certificate of Analysis | Jun 10, 2021 | A106232 | |
| Certificate of Analysis | Jun 10, 2021 | A106232 |
| Solubility | Soluble in water (18.2 g/100g @ 25C). Soluble in and acetate. Slightly soluble in carbon tetrachloride. |
|---|---|
| Sensitivity | light sensitive;air sensitive |
| Refractive Index | 1.52-1.522 |
| Flash Point(°F) | 76°C |
| Flash Point(°C) | 76°C |
| Boil Point(°C) | 188-189°C |
| Melt Point(°C) | 8-10°C |
| Molecular Weight | 121.140 g/mol |
| XLogP3 | 0.900 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 121.053 Da |
| Monoisotopic Mass | 121.053 Da |
| Topological Polar Surface Area | 30.000 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 111.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Xiaofang Fu, Zhuohui Zhang, Zhenhu Cao, Alexandr Alexandrovich Rogachev, Maxim Anatolievich Yarmolenko, Tao Chen, Hongtao Cao, Hongliang Zhang. (2023) Mechanistic Insights into Anion-Induced Electrochromism of Ru(II)-Based Metallo-Supramolecular Polymer. Polymers, 15 (24): (4735). [PMID:38139986] [10.3390/polym15244735] |
| 2. An Zhidong, Yang Piaoping, Duan Delong, Li Jiang, Wan Tong, Kong Yue, Caratzoulas Stavros, Xiang Shuting, Liu Jiaxing, Huang Lei, Frenkel Anatoly I., Jiang Yuan-Ye, Long Ran, Li Zhenxing, Vlachos Dionisios G.. (2023) Highly active, ultra-low loading single-atom iron catalysts for catalytic transfer hydrogenation. Nature Communications, 14 (1): (1-12). [PMID:37863924] [10.1038/s41467-023-42337-9] |
| 3. Tang Mingqiang, Chen Weijie, Liu Zewei, Pang Jun, Li Chaoping, Liu Sijie, Tan Rong. (2023) Zinc(terpyridine)-Incorporated Metal–Organic Frameworks Enabled Photocatalytic Oxidative Coupling of Amines Under Visible Light in Atmospheric Air. CATALYSIS LETTERS, [PMID:] [10.1007/s10562-023-04386-z] |
| 4. Xiaofeng Cui, Xueting Wang, Lijun Zhao, Jixin Wang, Tingting Kong, Yujie Xiong. (2023) Bridging molecular photosensitizer and catalyst on carbon nanotubes toward enhanced selectivity and durability for CO2 photoreduction. Journal of Environmental Sciences, [PMID:38331497] [10.1016/j.jes.2023.06.022] |
| 5. Shiyou Liu, Congyuan Wei, Han Wang, Weilong Yang, Jian Zhang, Zhuanpei Wang, Weili Zhao, Pooi See Lee, Guofa Cai. (2023) Processable nanoarchitectonics of two-dimensional metallo-supramolecular polymer for electrochromic energy storage devices with high coloration efficiency and stability. Nano Energy, [PMID:] [10.1016/j.nanoen.2023.108337] |
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| 7. Maowa Zhang, Haiqing Hao, Chenxi Shi, Chongchong Chen, Guoli Zhou, Jingtao Wang, Yijun Cao, Xiangke Han. (2023) Bis-terpyridine imprinted nanocage in the confined two-dimensional lamellar membrane for selective adsorption of Nd(III). SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2023.123095] |
| 8. Lina Guo, Xiaochao Chen, Ruijun Xie, Limin Han, Ning Zhu. (2022) 4-Phenyl-2-(2′-pyridyl) quinoline acts as a highly sensitive fluorescent probe for Fe2+ and Fe3+ ions and exhibits reversible photoelectric stimulation response. JOURNAL OF MOLECULAR STRUCTURE, [PMID:] [10.1016/j.molstruc.2022.134615] |
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| 10. Haiwen Li, Junhu Xin, Yuhang Xue, Cunde Wang. (2022) DBU-Mediated Domino Annulation Reaction of 2-Amino-4H-chromen-4-ones and Aromatic Aldehydes for Synthesis of Polysubstituted 3-Hydroxy-5H-chromeno[2,3-b]pyridinones. JOURNAL OF ORGANIC CHEMISTRY, [PMID:35960790] [10.1021/acs.joc.2c01152] |
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| 13. Zhang Na, Wu Yansong, Li Yuying, Chen Liduo, Zhang Mingshui, Wang Jun. (2021) Star iminopyridyl iron, cobalt and nickel complexes: synthesis, molecular structures, and evaluation as ethylene oligomerization catalysts. POLYMER BULLETIN, 79 (6): (4219-4231). [PMID:] [10.1007/s00289-021-03697-8] |
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| 19. Xiuquan Jia, Jiping Ma, Min Wang, Xiaofang Li, Jin Gao, Jie Xu. (2016) Alkali α-MnO2/NaxMnO2 collaboratively catalyzed ammoxidation–Pinner tandem reaction of aldehydes. Catalysis Science & Technology, 6 (20): (7429-7436). [PMID:] [10.1039/C6CY00874G] |
| 20. Rao Tongde, Liang Lijiao, Zhang Liying. (2013) Ratiometric Fluorescence Recognition for Pyrophosphate on the Basis of Terpyridine Derivative. ANALYTICAL SCIENCES, 29 (12): (1165-1169). [PMID:24334982] [10.2116/analsci.29.1165] |
| 21. Lina Guo, Ligang Yan, Ruijun Xie, Limin Han, Ning Zhu. (2025) A solvatochromic Pd(II) complex with AIEE property: Structural characteristics, chromotropic mechanism and its application in solvent detection. JOURNAL OF MOLECULAR STRUCTURE, [PMID:] [10.1016/j.molstruc.2025.141677] |
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