2'-Deoxyadenosine Anhydrous - Moligand™, ≥98%(HPLC)(T) , CAS No.958-09-8

CAS: 958-09-8 Cat. No.: D155667 Fórmula: C₁₀H₁₃N₅O₃ Peso molecular: 251.25 Número EC: 213-488-7

GRADE & PURITY Moligand™, ≥98%(HPLC)(T)

Synonyms

adenine-9 2-deoxy-b-D-erythro-Pentofuranoside | 9-(2-deoxy-b-D-ribofuranosyl)-9H-Purin-6-amine | NSC-141848 | P582C98ULC | beta-D-Ribofuranose, 1-(6-amino-9H-purin-9-yl)-1,2-dideoxy- | 5-(6-AMINO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL | 9-(2-De

Storage

Store at 2-8°C

Shipped In

Wet ice

Descripción general

2′-Deoxyadenosine, also called DNA nucleoside A, is a nucleoside adenosine derivative. 2′-Deoxyadenosine pairs with deoxythymidine (T) in double-stranded DNA. In absence of adenosine deaminase (ADA) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease (ADA-SCID).
A nucleoside adenosine derivative with mutagenic properties

Specifications

Sinónimos

adenine-9 2-deoxy-b-D-erythro-Pentofuranoside | 9-(2-deoxy-b-D-ribofuranosyl)-9H-Purin-6-amine | NSC-141848 | P582C98ULC | beta-D-Ribofuranose, 1-(6-amino-9H-purin-9-yl)-1,2-dideoxy- | 5-(6-AMINO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL | 9-(2-De

Especificaciones y pureza

Moligand™, ≥98%(HPLC)(T)

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Pureza

≥98%(HPLC)(T)

Nombres e identificadores

Pubchem Sid

504752486

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504752486

Sonrisas canónicas

C1C(C(OC1N2C=NC3=C(N=CN=C32)N)CO)O

IUPAC Name

(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

InChIKey

OLXZPDWKRNYJJZ-RRKCRQDMSA-N

INCHI

1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1

Isómeros SMILES

C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)O

RTECS

AU7358600

Peso molecular

251.25

Reaxy-Rn

621763

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=621763&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Clase Purine nucleosides
      • Subclass Purine 2'-deoxyribonucleosides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Clase: Purine nucleosides
• Subclass: Purine 2'-deoxyribonucleosides
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine 2'-deoxyribonucleosides
• Alternative Parents: 6-aminopurines Aminopyrimidines and derivatives N-substituted imidazoles Imidolactams Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary amines Primary alcohols Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine 2'-deoxyribonucleoside - 6-aminopurine - Imidazopyrimidine - Purine - Aminopyrimidine - N-substituted imidazole - Pyrimidine - Imidolactam - Azole - Imidazole - Heteroaromatic compound - Tetrahydrofuran - Secondary alcohol - Oxacycle - Azacycle - Organoheterocyclic compound - Amine - Primary amine - Primary alcohol - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Alcohol - Organic nitrogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as purine 2'-deoxyribonucleosides. These are compounds consisting of a purine linked to a ribose which lacks a hydroxyl group at position 2.
• External Descriptors: Deoxyribonucleosides

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

ADA Tclin Adenosine deaminase (129 Activities)

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ADORA1 Tclin Adenosine A1 receptor (17603 Activities)

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ADORA2A Tclin Adenosine A2a receptor (16305 Activities)

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ADORA2B Tclin Adenosine A2b receptor (7672 Activities)

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ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

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DCK Tchem Deoxycytidine kinase (530 Activities)

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TK1 Tchem Thymidine kinase, cytosolic (627 Activities)

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DU-145 (51482 Activities)

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MCF7 (126967 Activities)

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MT4 (17854 Activities)

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ATH-8 cell line (300 Activities)

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HaCaT (4069 Activities)

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HEL (6614 Activities)

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HeLa (62764 Activities)

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

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Objetivos asociados (no humanos)

Adcy5 Adenylate cyclase type V (89 Activities)

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Trichomonas vaginalis (2376 Activities)

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Human alphaherpesvirus 2 (4932 Activities)

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Human respirovirus 3 (1674 Activities)

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Vaccinia virus (4609 Activities)

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Human alphaherpesvirus 1 (11089 Activities)

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Hepatitis B virus (7925 Activities)

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Human immunodeficiency virus 1 (70413 Activities)

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Poliovirus 1 (1274 Activities)

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Semliki Forest virus (705 Activities)

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Sindbis virus (1599 Activities)

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Vesicular stomatitis virus (4460 Activities)

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Coxsackievirus B4 (2249 Activities)

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Respiratory syncytial virus (3434 Activities)

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Duck hepatitis B virus (235 Activities)

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MDCK (10148 Activities)

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C6 (2371 Activities)

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L6 (7924 Activities)

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dak Deoxyadenosine kinase (12 Activities)

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Mammalian orthoreovirus 1 (1523 Activities)

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Woodchuck hepatitis virus (122 Activities)

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Mecanismos de acción

Propiedades químicas y físicas

• Sensibilidad: Air Sensitive,Heat Sensitive
• Rotación específica [α]: -27° (C=0.5,H2O)
• Punto de fusión (°C): 191 °C
• Peso molecular: 251.240 g/mol
• XLogP3: -0.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 251.102 Da
• Monoisotopic Mass: 251.102 Da
• Topological Polar Surface Area: 119.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 307.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Preguntas frecuentes

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 958-09-8, the molecular formula is C10H13N5O3, and the molecular weight is 251.25 g/mol. InChIKey OLXZPDWKRNYJJZ-RRKCRQDMSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.