(2-Hydroxypropyl)-γ-cyclodextrin(HP-γ-CD) - average Mw ~1,580 , CAS No.128446-34-4

CAS: 128446-34-4 Cat. No.: H102030
AVAILABLE TO ORDER
GRADE & PURITY average Mw ~1,580
Synonyms
A7090 | 2-Fluoro-4-methyl-1-nitrobenzene | 2-fluoro-4-methyl-1-nitro-benzene | NSC 25756 | 2-Fluoro-4-methyl-1-nitrobenzene # | AC-13799 | MFCD00007053 | DTXSID6060002 | F0567 | SCHEMBL247992 | gamma-Cyclodextrin, 2-hydroxypropyl ethers | Benzene, 2-fluor
Storage
Room temperature,Desiccated,Cool
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1g
H102030-1g
3
$9.90
5g
H102030-5g
5
$29.90
25g
H102030-25g
4
$59.90
100g
H102030-100g
3
$175.90
Enter a quantity for the sizes you want to add.
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Why this grade

average Mw ~1,580 for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature,Desiccated,Cool Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

(2-Hydroxypropyl)-γ-cyclodextrin (HP-β-CD) is a hydrophilic compound that can be used as a complexing agent to increase the aqueous solubility and dissolution rate of the drug molecule.
HP-β-CD can be utilized to improve the aqueous solubility and dissolution rate of zolpidem (ZP) upon complexation. ZP-HP-β-CD complexes showed improved ataxic activity.
It is also used to enhance the wound healing property of curcumin by increasing the water solubility.

Specifications

Synonyms
A7090 | 2-Fluoro-4-methyl-1-nitrobenzene | 2-fluoro-4-methyl-1-nitro-benzene | NSC 25756 | 2-Fluoro-4-methyl-1-nitrobenzene # | AC-13799 | MFCD00007053 | DTXSID6060002 | F0567 | SCHEMBL247992 | gamma-Cyclodextrin, 2-hydroxypropyl ethers | Benzene, 2-fluor
Specifications & Purity
average Mw ~1, 580
Storage
Room temperature, Desiccated, Cool
Shipped In
Normal
Names and Identifiers
Pubchem Sid504754228
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504754228
Canonical SmilesCC1=CC(=C(C=C1)[N+](=O)[O-])F
IUPAC Name2-fluoro-4-methyl-1-nitrobenzene
InChIKeyWZMOWQCNPFDWPA-UHFFFAOYSA-N
INCHI1S/C7H6FNO2/c1-5-2-3-7(9(10)11)6(8)4-5/h2-4H,1H3
Isomeric SMILES CC1=CC(=C(C=C1)[N+](=O)[O-])F
WGK Germany 3
Reaxy-Rn 2502584
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2502584&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

16 results found

Lot NumberCertificate TypeDateItem
E2612372Certificate of AnalysisApr 22, 2026 H102030
E2612373Certificate of AnalysisApr 22, 2026 H102030
K2514662Certificate of AnalysisNov 01, 2025 H102030
K2514665Certificate of AnalysisNov 01, 2025 H102030
K2514666Certificate of AnalysisNov 01, 2025 H102030
K2524739Certificate of AnalysisNov 01, 2025 H102030
L2115384Certificate of AnalysisSep 17, 2025 H102030
J1915046Certificate of AnalysisJul 31, 2023 H102030
G2319569Certificate of AnalysisJul 27, 2023 H102030
E1914001Certificate of AnalysisMar 08, 2023 H102030
E2515113Certificate of AnalysisJul 25, 2022 H102030
G2319545Certificate of AnalysisJul 25, 2022 H102030
K2204401Certificate of AnalysisJul 25, 2022 H102030
K2204402Certificate of AnalysisJul 25, 2022 H102030
K2204541Certificate of AnalysisJul 25, 2022 H102030
K2204542Certificate of AnalysisJul 25, 2022 H102030

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Chemical and Physical Properties
SolubilityH2O: 450 mg/mL
Molecular Weight155.130 g/mol
XLogP32.200
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass155.038 Da
Monoisotopic Mass155.038 Da
Topological Polar Surface Area45.800 Ų
Heavy Atom Count11
Formal Charge0
Complexity157.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Zhiwei Shi, Weiping Li, Azhu Wang, Yuzhe Wang, Huishi Pi, Huicong Liu, Haining Chen, Pei Li, Xiaoyu Jiang.  (2023)  Inclusion Complexes of Photosensitizers with Cyclodextrins for Enhancing the Fabrication of Volume Grating.  ACS Applied Materials & Interfaces,      [PMID:36790868] [10.1021/acsami.2c21905]
2. Qian Shi, Yuanyuan Wu, Yunyun Xu, Min Bao, Xiao Chen, Kui Huang, Qiulan Yang, Yang Yang.  (2023)  Virus Mimetic Framework DNA as a Non-LNP Gene Carrier for Modulated Cell Endocytosis and Apoptosis.  ACS Nano,      [PMID:36693051] [10.1021/acsnano.2c09772]
3. Li Zhe, Jiang Xiaoxia, Zhu Lin, Chen Fucai, Liu Hongning, Ming Liangshan.  (2022)  New insights into the thermal degradation behavior of Hydroxypropyl-beta-cyclodextrin inclusion complexes containing carvacrol essential oil via thermogravimetric analysis.  JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY,  147  (20): (11301-11312).  [PMID:] [10.1007/s10973-022-11327-2]
4. Shengmei Wang, Xuanjun Liu, Shengfeng Wang, Linqi Ouyang, Hui Li, Jinsong Ding, Guiming Deng, Wenhu Zhou.  (2021)  Imatinib co-loaded targeted realgar nanocrystal for synergistic therapy of chronic myeloid leukemia.  JOURNAL OF CONTROLLED RELEASE,      [PMID:34428479] [10.1016/j.jconrel.2021.08.035]
5. Shuang Gao, Jingyu Jiang, Xiaoming Li, Fei Ye, Ying Fu, Lixia Zhao.  (2021)  Electrospun Polymer-Free Nanofibers Incorporating Hydroxypropyl-β-cyclodextrin/Difenoconazole via Supramolecular Assembly for Antifungal Activity.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:34013730] [10.1021/acs.jafc.1c01351]
6. Ruihao Yang, Mengmeng Hou, Ya Gao, Shiyu Lu, Lei Zhang, Zhigang Xu, Chang Ming Li, Yuejun Kang, Peng Xue.  (2019)  Biomineralization-inspired Crystallization of Manganese Oxide on Silk Fibroin Nanoparticles for in vivo MR/fluorescence Imaging-assisted Tri-modal Therapy of Cancer.  Theranostics,      [PMID:31534553] [10.7150/thno.36252]
7. Xinyu Bian, Bing Zhao, Bo Pang, Zhong Zheng, Shu Liu, Zhiqiang Liu, Fengrui Song.  (2019)  Separation, Quantification and Structural Study of (+)-Catechin and (–)-Epicatechin by Ion Mobility Mass Spectrometry Combined with Theoretical Algorithms.  CHINESE JOURNAL OF CHEMISTRY,  37  (6): (581-587).  [PMID:] [10.1002/cjoc.201900057]
8. Xue Li, Chengpeng Li, Sheng Wang, Huan Dong, Xiang Ma, Derong Cao.  (2017)  Synthesis and properties of photochromic spirooxazine with aggregation-induced emission fluorophores polymeric nanoparticles.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2017.03.068]
9. Lanxiang Liu, Juan Xu, Hua Zheng, Kun Li, Wenwen Zhang, Kai Li, Hong Zhang.  (2017)  Inclusion complexes of laccaic acid A with β-cyclodextrin or its derivatives: Phase solubility, solubilization, inclusion mode, and characterization.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2017.01.001]
10. Ma Xiao-Hong, Zhao Ling, Lin Zhi-Rong, Dong Yuan-Hua.  (2016)  Soil washing in combination with homogeneous Fenton-like oxidation for the removal of 2,4,4′-trichlorodiphenyl from soil contaminated with capacitor oil.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  23  (8): (7890-7898).  [PMID:26762933] [10.1007/s11356-016-6037-2]
11. Fengrui Li, Yue Xiu, Anqi Wang, Yuhang Zhang, Xinyue Zhang, Shuang Gao, Fei Ye, Ying Fu.  (2025)  Environmentally Friendly Sustained-Release Antifungal Cyclodextrin Inclusion Complex Nanofibers for Controlling Fungi.  LANGMUIR,      [PMID:40016198] [10.1021/acs.langmuir.5c00158]
12. Wenfei Wang, Menglu Duan, Fei Li, Yanhui He, Runze Li, Qinhui He, Yuan Deng, Xiaofang Zhang, Jiao Li.  (2025)  In silico prediction of the formation, solubilization, and stabilization of a cyclodextrin-based ternary complex of ivermectin using long-timescale molecular dynamics simulations.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2025.128993]
Solution Calculators
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