3,4-Difluorobenzylidene curcumin(CDF) - Moligand™,≥98% , CAS No.1170354-22-9

CAS: 1170354-22-9 Cat. No.: D276377 Molecular Weight: 492.47

GRADE & PURITY Moligand™, ≥98%

Synonyms

(1E,6E)-4-[(3,4-Difluorophenyl)methylidene]-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione | Difluorinated Curcumin | 4-(3,4-Difluorobenzo)curcumin

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Difluorinated Curcumin (3,4-Difluorobenzylidene curcumin) is a fluorinated curcumin analog with high bioavailability and anticancer activity. Difluorinated Curcumin inhibits the self-renewal ability of tumor stem/stem-like cells, clonogenicity, invasiveness and angiogenesis of tumor cells. Difluorinated Curcumin also increases cell sensitivity to chemotherapy.

Specifications

Synonyms

(1E, 6E)-4-[(3, 4-Difluorophenyl)methylidene]-1, 7-bis(4-hydroxy-3-methoxyphenyl)hepta-1, 6-diene-3, 5-dione | Difluorinated Curcumin | 4-(3, 4-Difluorobenzo)curcumin

Specifications & Purity

Moligand™, ≥98%

Biochemical and Physiological Mechanisms

Lipoxygenase and cyclooxygenase inhibitor. Able to induce apoptosis. Antioxidant and anti-inflammatory properties.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥98%

Names and Identifiers

• Molecular Weight: 492.47