4-Hydroxybenzenesulfonamide - ≥97% , CAS No.1576-43-8

CAS: 1576-43-8 Cat. No.: H138312 Molecular Weight: 173.19 EC Number: 216-408-9
AVAILABLE TO ORDER
GRADE & PURITY ≥97%
Synonyms
Benzenesulfonamide, 4-hydroxy- | BP-10587 | SY045622 | p-Hydroxy-benzene derivative, 3a | 1IIT7R7VPJ | 4-Hydroxybenzenesulfonamide | K4N | Z360053740 | 1-(2-Furyl)ethanone | 1-PHENOL-4-SULFONAMIDE | 4-Sulfamoylphenol | QY3BV00PCY | AB01206063-03 | NSC2084
Storage
Argon charged,Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1g
H138312-1g
5

$9.90

$14.90
Save $5.00 (33.56%)
5g
H138312-5g
3

$21.90

$32.90
Save $11.00 (33.43%)
25g
H138312-25g
2

$79.90

$119.90
Save $40.00 (33.36%)
100g
H138312-100g
1

$255.90

$383.90
Save $128.00 (33.34%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Benzenesulfonamide, 4-hydroxy- | BP-10587 | SY045622 | p-Hydroxy-benzene derivative, 3a | 1IIT7R7VPJ | 4-Hydroxybenzenesulfonamide | K4N | Z360053740 | 1-(2-Furyl)ethanone | 1-PHENOL-4-SULFONAMIDE | 4-Sulfamoylphenol | QY3BV00PCY | AB01206063-03 | NSC2084
Specifications & Purity
≥97%
Storage
Argon charged, Room temperature
Shipped In
Normal
Purity
≥97%
Names and Identifiers
Pubchem Sid488184866
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488184866
Canonical SmilesC1=CC(=CC=C1O)S(=O)(=O)N
IUPAC Name4-hydroxybenzenesulfonamide
InChIKeyDIRCLGLKRZLKHG-UHFFFAOYSA-N
INCHI1S/C6H7NO3S/c7-11(9,10)6-3-1-5(8)2-4-6/h1-4,8H,(H2,7,9,10)
Isomeric SMILES C1=CC(=CC=C1O)S(=O)(=O)N
Molecular Weight 173.19
Reaxy-Rn 1869258
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1869258&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassBenzenesulfonamides
Intermediate Tree Nodes Not available
Direct ParentBenzenesulfonamides
Alternative Parents Benzenesulfonyl compounds  1-hydroxy-2-unsubstituted benzenoids  Organosulfonamides  Aminosulfonyl compounds  Organooxygen compounds  Organic oxides  Organic nitrogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Benzenesulfonamide - Benzenesulfonyl group - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Organosulfonic acid amide - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Aminosulfonyl compound - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Organooxygen compound - Organosulfur compound - Hydrocarbon derivative - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CA1 Tclin Carbonic anhydrase 1 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase 2 (16 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA12 Tclin Carbonic anhydrase 12 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA9 Tclin Carbonic anhydrase 9 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ca1 Delta carbonic anhydrase (40 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
F2327245Certificate of AnalysisJul 03, 2023 H138312
F2327338Certificate of AnalysisJul 03, 2023 H138312
F2327342Certificate of AnalysisJul 03, 2023 H138312
F2327344Certificate of AnalysisJul 03, 2023 H138312
F2327345Certificate of AnalysisJul 03, 2023 H138312
F2327348Certificate of AnalysisJul 03, 2023 H138312
F2327349Certificate of AnalysisJul 03, 2023 H138312
F2327355Certificate of AnalysisJul 03, 2023 H138312
F2327359Certificate of AnalysisJul 03, 2023 H138312
Chemical and Physical Properties
SolubilitySolubility in Methanol very faint turbidity
Melt Point(°C)174 - 178.0 °C
Molecular Weight173.190 g/mol
XLogP30.100
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass173.015 Da
Monoisotopic Mass173.015 Da
Topological Polar Surface Area88.800 Ų
Heavy Atom Count11
Formal Charge0
Complexity210.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Shumin Hu, Qiuli Cheng, Yulu Shang, Zhihao Wang, Rui Zhu, Leitao Zhang, Wenlan Wu, Shouren Zhang, Junbo Li.  (2023)  Synthesis of pH-responsive polyzwitterions for activated cellular uptake and tumor accumulation of gold nanoparticles at tumorous acidity.  Biomedical Materials,  18  (2): (025003).  [PMID:36645918] [10.1088/1748-605X/acb394]
2. Shang-Xiong Wei, Yu-Hang Yang, Xue-Bo Liu, Xiao-Bin Ye, Xiao-Peng Zhao, Xue-Wei Pi, Xue-Feng Cheng, Jing-Hui He.  (2025)  Laser-induced PdCu alloy catalysts for highly efficient and stable electrocatalytic nitrate reduction to ammonia.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:40056684] [10.1016/j.jcis.2025.02.210]
Solution Calculators
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