8-Bromo-cAMP - 10mM in DMSO , CAS No.76939-46-3

CAS: 76939-46-3 Cat. No.: B407933 Fórmula: C₁₀H₁₀BrN₅NaO₆P Peso molecular: 430.08

GRADE & PURITY 10mM in DMSO

Synonyms

8-Br-Camp | 8-bromoadenosine 3',5'-cyclic monophosphate sodium salt

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

8-Bromo-cAMP 8-bromo-cAMP (8-Br-Camp) is a cell permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0.05 μM; and a PKA activator.
In vitro

8-Bromo-cAMP improves the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells. In bronchial epithelial cells, 8-Bromo-cAMP decreases HDE-stimulated tumor necrosis factor (TNF)-α-converting enzyme (TACE; ADAM-17) activity and subsequent TNF-α release.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

8-Br-Camp | 8-bromoadenosine 3',5'-cyclic monophosphate sodium salt

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

8-bromo-cAMP (8-Br-Camp) is a cell permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0.05 μM; and a PKA activator.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Isómeros SMILES: C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=NC=NC(=C4N=C3Br)N)O)OP(=O)(O1)[O-].[Na+]
• Peso molecular: 430.08
• Reaxy-Rn: 26039674
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=26039674&ln=

Preguntas frecuentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 76939-46-3, the molecular formula is C10H10BrN5NaO6P, and the molecular weight is 430.08 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.