Acevaltrate - ≥99% , CAS No.25161-41-5

CAS: 25161-41-5 Cat. No.: A649443 Fórmula: C₂₄H₃₂O₁₀ Peso molecular: 480.50 PubChem CID: 65717

CALIDAD & PUREZA ≥99%

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Acevaltrate inhibits the Na + / K + -ATPase activity in the rat kidney and brain hemispheres with IC 50 s of 22.8 μM and 42.3 μM, respectively

In Vitro

Acevaltrate differentiallys inhibit the activity of rat P-type ATPases in vitro. 60.7±7.3% inhibition of the rat H + /K + -ATPase is achieved at 100 µM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 22.8±1.1 μM (Na + /K + -ATPase, in rat kidney), 42.3±1.0 μM (Na + /K + -ATPase, in rat brain hemispheres)

Especificaciones

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

Acevaltrate inhibits the Na + / K + -ATPase activity in the rat kidney and brain hemispheres with IC 50 s of 22.8 μM and 42.3 μM, respectively.

Condiciones de almacenamiento de almacenamiento

Protected from light,Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥99%

Nombres e identificadores

Isómeros SMILES

CC(C)CC(=O)O[C@H]1[C@H]2C(=C[C@@H]([C@]23CO3)OC(=O)CC(C)(C)OC(=O)C)C(=CO1)COC(=O)C

PubChem CID

65717

Peso molecular

480.50

Objetivos asociados (humanos)

HCT-8 (3484 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A549 (127892 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: DMSO : 100 mg/mL (208.12 mM; Need ultrasonic)
• Peso molecular: 480.500 g/mol
• XLogP3: 0.900
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 13
• Exact Mass: 480.2 Da
• Monoisotopic Mass: 480.2 Da
• Topological Polar Surface Area: 127.000 Ų
• Heavy Atom Count: 34
• Formal Charge: 0
• Complexity: 915.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1