Alfacalcidol - 10mM in DMSO , Vitamin D receptor agonist, CAS No.41294-56-8, Vitamin D receptor agonist

CAS: 41294-56-8 Cat. No.: A408978 Molecular Weight: 400.64 EC Number: 255-297-1

GRADE & PURITY 10mM in DMSO

Synonyms

1-hydroxycholecalciferol | (1R,3S,E)-5-((Z)-2-((1R,3aS,7aR)-7a-methyl-1-((R)-6-methylheptan-2-yl)-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Alfacalcidol Alfacalcidol (1-hydroxycholecalciferol) is a non-selective VDR activator medication.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Synonyms

1-hydroxycholecalciferol | (1R, 3S, E)-5-((Z)-2-((1R, 3aS, 7aR)-7a-methyl-1-((R)-6-methylheptan-2-yl)-octahydroinden-4-ylidene)ethylidene)-4-methylenecyclohexane-1, 3-diol

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Alfacalcidol (1-hydroxycholecalciferol) is a non-selective VDR activator medication.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

AGONIST

Mechanism of action

Vitamin D receptor agonist

Product Properties

• ALogP: 6.8

Names and Identifiers

• Isomeric SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C
• WGK Germany: 3
• RTECS: VS2851000
• Molecular Weight: 400.64
• Reaxy-Rn: 36250914
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=36250914&ln=

Associated Targets(Human)

SLC6A2 Tclin Sodium-dependent noradrenaline transporter (2 Activities)

Discover Target: SLC6A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemical and Physical Properties

• Specific Rotation[α]: 36° (C=0.3,CHCl3)
• Melt Point(°C): 136 °C