Allylthiourea - 10mM in DMSO , CAS No.109-57-9

CAS: 109-57-9 Cat. No.: A408879 Fórmula: C₄H₈N₂S Peso molecular: 116.18 Beilstein Registry Number: 1071470 Número EC: 203-683-5

GRADE & PURITY 10mM in DMSO

Synonyms

Thiourea, N-2-propen-1-yl-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Allylthiourea Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation .
In vitro

Allylthiourea selectively inhibits ammonia oxidation at concentrations 8-80 μM. Allylthiourea (1 μM)inhibits ammonia oxidation by 80%. Complete inhibition is observed at an Allylthiourea concentration of 86 μM. The inhibition of Allylthiourea on ammonia oxidation probably acts through chelating the copper of the ammonia monooxygenase active site. Allylthiourea is able to produce soluble methane monooxygenase (sMMO) in the presence of copper. Addition of 25 μM Allylthiourea decreases intracellular copper by 48% in Methylosinus trichosporium OB3b, allowing sMMO production at Cu/biomass ratios normally not permitting sMMO synthesis, which achieves a plateau of 320 μmol naphthol formed per gram dry biomass per hour.

In vivo

Cell Data

cell lines：HeLa, HCT-116, A375, SK-OV-3, MDA-MB-231, and PC-3 cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

Thiourea, N-2-propen-1-yl-

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

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Nombres e identificadores

• Isómeros SMILES: C=CCNC(=S)N
• WGK Alemania: 3
• RTECS: YR8050000
• Número ONU: 2811
• Grupo de embalaje: I
• Peso molecular: 116.18
• Beilstein: 1071470
• Reaxy-Rn: 1071470
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1071470&ln=

Propiedades químicas y físicas

• Punto de fusión (°C): 70-72°C

Preguntas frecuentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 109-57-9, the molecular formula is C4H8N2S, and the molecular weight is 116.18 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.