Amitriptyline-d6 Hydrochloride - ≥99 atom% D,≥98% , CAS No.203645-63-0

CAS: 203645-63-0 Cat. No.: A357463 Fórmula: C₂₀H₁₈D₆ClN Peso molecular: 319.90 Número EC: 846-446-7

GRADE & PURITY ≥99 atom% D,≥98%

Synonyms

3-(5,6-dihydrodibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride | 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine-d6 Hydrochloride

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Descripción general

Amitriptyline-d6 (hydrochloride) is the deuterium labeled Amitriptyline hydrochloride. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity

Specifications

Sinónimos

3-(5,6-dihydrodibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride | 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine-d6 Hydrochloride

Especificaciones y pureza

≥99 atom% D,≥98%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C,Protected from light

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥99 atom% D,≥98%

Nombres e identificadores

• Pubchem Sid: 528773940
• Sonrisas canónicas: CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
• IUPAC Name: 3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride
• InChIKey: KFYRPLNVJVHZGT-TXHXQZCNSA-N
• INCHI: 1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H/i1D3,2D3
• Isómeros SMILES: [2H]C([2H])([2H])N(CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31)C([2H])([2H])[2H].Cl
• CAS alternativo: 549-18-8（Unlabelled ）
• Número ONU: 2811
• Grupo de embalaje: III
• Peso molecular: 319.90
• Reaxy-Rn: 4164595
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4164595&ln=

Propiedades químicas y físicas

• Sensibilidad: Light sensitive；Moisture sensitive
• Punto de fusión (°C): 192-195° C