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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications
Product Name
Astressin 2B, CAS No.681260-70-8
Synonyms
astressin-2B | Cyclo(31-34)(Phe(11), His(12), CMeLeu(13, 39), Nle(17), Glu(31), Lys(34)) Ac-sauvagine (8-40) | cyclo(31-34)(Phe11, His12, CMeLeu13, 39, Nle17, Glu31, Lys34) Ac-sauvagine(8-40) | ASTRESSIN 2B
Biochemical and Physiological Mechanisms
Potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist (IC50values are 1.3 and > 500 nM for CRF2and CRF1respectively). Antagonizes CRF2-mediated inhibition of gastric emptying.
Sequence
DLSFHLLRKXIEIEKQEKEKQQAENNKLLLDLI(Modifications: Asp-1 = N-terminal Ac, Phe-4 = D-Phe, Leu-6 = α-methyl-Leu, X = Nle, Glu-24 = γ-Glu, Lys-27 = ε-Lys, Leu-32 = α-methyl-Leu, Lactam Bridge = Glu-24 - Lys-27)
Action Type
ANTAGONIST
CAS
681260-70-8
Molecule Type
Bioreagents/Buffer
Storage and Shipping
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
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