AVE1231 - Moligand™, ≥98% , Channel blocker of K 2P3.1, CAS No.767334-89-4, Channel blocker of K 2P3.1

CAS: 767334-89-4 Cat. No.: A607819 Molecular Weight: 405.51 PubChem CID: 9844211

GRADE & PURITY Moligand™, ≥98%

Synonyms

SCHEMBL498598 | VGZ6BSQ5DR | 2-(butylsulfonylamino)-N-[(1R)-1-(6-methoxypyridin-3-yl)propyl]benzamide | Benzamide, 2-((butylsulfonyl)amino)-N-((1R)-1-(6-methoxy-3-pyridinyl)propyl)- | UNII-VGZ6BSQ5DR | A293 | A-293 | AVE1231 | AVE-1231 | GTPL11206 | (R)-2

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

AVE1231 is an atrial-selective antiarrhythmic human cardiac Kv1.5 inhibitor.

Specifications

Synonyms

SCHEMBL498598 | VGZ6BSQ5DR | 2-(butylsulfonylamino)-N-[(1R)-1-(6-methoxypyridin-3-yl)propyl]benzamide | Benzamide, 2-((butylsulfonyl)amino)-N-((1R)-1-(6-methoxy-3-pyridinyl)propyl)- | UNII-VGZ6BSQ5DR | A293 | A-293 | AVE1231 | AVE-1231 | GTPL11206 | (R)-2

Specifications & Purity

Moligand™, ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

CHANNEL BLOCKER

Mechanism of action

Channel blocker of K 2P3.1

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 528763178
• Canonical Smiles: CCCCS(=O)(=O)Nc1ccccc1C(=O)N[C@@H](c1ccc(nc1)OC)CC
• IUPAC Name: 2-(butylsulfonylamino)-N-[(1R)-1-(6-methoxypyridin-3-yl)propyl]benzamide
• InChIKey: BFQMQSIBOHOPCY-QGZVFWFLSA-N
• INCHI: 1S/C20H27N3O4S/c1-4-6-13-28(25,26)23-18-10-8-7-9-16(18)20(24)22-17(5-2)15-11-12-19(27-3)21-14-15/h7-12,14,17,23H,4-6,13H2,1-3H3,(H,22,24)/t17-/m1/s1
• Isomeric SMILES: CCCCS(=O)(=O)NC1=CC=CC=C1C(=O)N[C@H](CC)C2=CN=C(C=C2)OC
• PubChem CID: 9844211
• Molecular Weight: 405.51

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Sulfanilides

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Sulfanilides
• Intermediate Tree Nodes: Not available
• Direct Parent: Sulfanilides
• Alternative Parents: Benzamides Benzoyl derivatives Alkyl aryl ethers Pyridines and derivatives Organosulfonamides Organic sulfonamides Vinylogous amides Heteroaromatic compounds Aminosulfonyl compounds Secondary carboxylic acid amides Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Sulfanilide - Benzamide - Benzoic acid or derivatives - Benzoyl - Alkyl aryl ether - Pyridine - Organosulfonic acid amide - Organic sulfonic acid amide - Heteroaromatic compound - Vinylogous amide - Aminosulfonyl compound - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Azacycle - Carboxylic acid derivative - Ether - Organoheterocyclic compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Organic oxide - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as sulfanilides. These are organic aromatic compounds containing a sulfanilide moiety, with the general structure RS(=O)(=O)NC1=CC=CC=C1.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

KCNK3 Tclin Potassium channel subfamily K member 3 (0 Activities)

Discover Target: KCNK3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)