AZD7268 - Moligand™ , Delta opioid receptor agonist, CAS No.A607883, Delta opioid receptor agonist

CAS: A607883 Cat. No.: A607883 PubChem CID: 24772484

GRADE & PURITY Moligand™

Synonyms

1018988-00-5 | N-(2-hydroxyethyl)-N-methyl-4-[quinolin-8-yl-[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl]benzamide | AZ 12488024 | Q27074783 | BENZAMIDE, N-(2-HYDROXYETHYL)-N-METHYL-4-(8-QUINOLINYL(1-(4-THIAZOLYLMETHYL)-4-PIPERIDINYLIDENE)METHYL)

Storage

Room temperature

Specifications

Synonyms

1018988-00-5 | N-(2-hydroxyethyl)-N-methyl-4-[quinolin-8-yl-[1-(1, 3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl]benzamide | AZ 12488024 | Q27074783 | BENZAMIDE, N-(2-HYDROXYETHYL)-N-METHYL-4-(8-QUINOLINYL(1-(4-THIAZOLYLMETHYL)-4-PIPERIDINYLIDENE)METHYL)

Specifications & Purity

Moligand™

Storage

Room temperature

Grade

Moligand™

Action Type

AGONIST

Mechanism of action

Delta opioid receptor agonist

Names and Identifiers

• Canonical Smiles: OCCN(C(=O)c1ccc(cc1)C(=C1CCN(CC1)Cc1cscn1)c1cccc2c1nccc2)C
• IUPAC Name: N-(2-hydroxyethyl)-N-methyl-4-[quinolin-8-yl-[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl]benzamide
• InChIKey: ZJKUETLEJYCOBO-UHFFFAOYSA-N
• INCHI: 1S/C29H30N4O2S/c1-32(16-17-34)29(35)24-9-7-21(8-10-24)27(26-6-2-4-23-5-3-13-30-28(23)26)22-11-14-33(15-12-22)18-25-19-36-20-31-25/h2-10,13,19-20,34H,11-12,14-18H2,1H3
• Isomeric SMILES: CN(CCO)C(=O)C1=CC=C(C=C1)C(=C2CCN(CC2)CC3=CSC=N3)C4=CC=CC5=C4N=CC=C5
• PubChem CID: 24772484

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Quinolines and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Quinolines and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Quinolines and derivatives
• Alternative Parents: Benzamides Benzoyl derivatives Aralkylamines Pyridines and derivatives Piperidines Thiazoles Tertiary carboxylic acid amides Heteroaromatic compounds Trialkylamines Amino acids and derivatives Azacyclic compounds Alkanolamines Primary alcohols Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Quinoline - Benzamide - Benzoic acid or derivatives - Benzoyl - Aralkylamine - Monocyclic benzene moiety - Piperidine - Pyridine - Benzenoid - Thiazole - Tertiary carboxylic acid amide - Heteroaromatic compound - Azole - Tertiary amine - Amino acid or derivatives - Tertiary aliphatic amine - Carboxamide group - Carboxylic acid derivative - Azacycle - Alkanolamine - Organonitrogen compound - Organic oxide - Organic oxygen compound - Alcohol - Organic nitrogen compound - Hydrocarbon derivative - Organooxygen compound - Primary alcohol - Amine - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as quinolines and derivatives. These are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

OPRD1 Tclin Delta-type opioid receptor (2 Activities)

Discover Target: OPRD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRM1 Tclin Mu opioid receptor (19785 Activities)

Discover Target: OPRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRD1 Tclin Delta opioid receptor (15096 Activities)

Discover Target: OPRD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action