Azido-PEG2-C2-acid - ≥97% , CAS No.1312309-63-9

CAS: 1312309-63-9 Cat. No.: A412755 Fórmula: C₇H₁₃N₃O₄ Peso molecular: 203.20

CALIDAD & PUREZA ≥97%

Synonyms

3-(2-(2-azidoethoxy)ethoxy)propanoic acid | N3-PEG2-CH2CH2COOH | Azido-PEG2-acid | Azido-PEG2-propionic acid | 9-Azido-4,7-dioxanonanoic acid | HY-140452 | Azido-PEG2-C2-acid | LCZC592 | 1312309-63-9 | ZB0916 | C70430 | 3-[2-(2-azidoethoxy)ethoxy]propanoi

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

Antibody Drug Conjugates(ADC), Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

Descripción general

Azido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG2-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Especificaciones

Sinónimos

3-(2-(2-azidoethoxy)ethoxy)propanoic acid | N3-PEG2-CH2CH2COOH | Azido-PEG2-acid | Azido-PEG2-propionic acid | 9-Azido-4,7-dioxanonanoic acid | HY-140452 | Azido-PEG2-C2-acid | LCZC592 | 1312309-63-9 | ZB0916 | C70430 | 3-[2-(2-azidoethoxy)ethoxy]propanoi

Especificaciones y pureza

≥97%

Mecanismos bioquímicos y fisiológicos

Azido-PEG2-C2-acid is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥97%

Nombres e identificadores

Pubchem Sid

508812860

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508812860

Sonrisas canónicas

C(COCCOCCN=[N+]=[N-])C(=O)O

IUPAC Name

3-[2-(2-azidoethoxy)ethoxy]propanoic acid

InChIKey

IEHDSRSXQAOLJT-UHFFFAOYSA-N

INCHI

1S/C7H13N3O4/c8-10-9-2-4-14-6-5-13-3-1-7(11)12/h1-6H2,(H,11,12)

Isómeros SMILES

C(COCCOCCN=[N+]=[N-])C(=O)O

Peso molecular

203.20

Reaxy-Rn

21362416

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21362416&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic 1,3-dipolar compounds
    • Clase Allyl-type 1,3-dipolar organic compounds
      • Subclass Azo imides

• Kingdom: Organic compounds
• Superclass: Organic 1,3-dipolar compounds
• Clase: Allyl-type 1,3-dipolar organic compounds
• Subclass: Azo imides
• Intermediate Tree Nodes: Not available
• Direct Parent: Azo imides
• Alternative Parents: Azo compounds Monocarboxylic acids and derivatives Dialkyl ethers Carboxylic acids Organopnictogen compounds Organic zwitterions Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Azo imide - Azo compound - Monocarboxylic acid or derivatives - Ether - Dialkyl ether - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic zwitterion - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as azo imides. These are n-Imides of azo compounds, analogous to azoxy compounds, having a delocalized structure.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro
• Peso molecular: 203.200 g/mol
• XLogP3: 0.300
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 9
• Exact Mass: 203.091 Da
• Monoisotopic Mass: 203.091 Da
• Topological Polar Surface Area: 70.100 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 203.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1