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Description
This heterobifunctional, PEGylated crosslinker 17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG5-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC®molecules) fortargeted protein degradation.
| CAS | 217180-81-9 |
|---|---|
| Sinónimos | Azido-PEG5-acid |
| Especificaciones y pureza | ≥95% |
| Condiciones de almacenamiento de almacenamiento | Store at 2-8°C,Argon charged |
| Enviado en | Wet ice |
| Product Description | Description This heterobifunctional, PEGylated crosslinker 17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG5-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC®molecules) fortargeted protein degradation. |
| Pubchem Sid | 488202577 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488202577 |
| Sensibilidad | moisture sensitive |
| Número Mdl | MFCD31561141 |
| PubChem CID | 99129378 |
| Fórmula molecular | C12H23N3O7 |