Bcl-2-IN-20 , CAS No.B1418059
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B1418059
Bcl-2-IN-20 (Compound 81) is an inhibitor for Bcl-2 with IC 50 <10 μM (79.1% inhibition at 9 μM). Bcl-2-IN-20 exhibits cytotoxicity in SK-MEL-28 ( IC 50 >10 μM), A549 ( IC 50 =6.1 μM), HepG2 ( IC 50 >10 μM), MCF-7 ( IC 50 =8.9 μM), HCT116 ( IC 50 >10 μM) and HEK-293 ( IC 50 =14.1 μM). Bcl-2-IN-20 promotes the ROS production, induces apoptosis and DNA damage.
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| CAS | B1418059 |
|---|---|
| Condiciones de almacenamiento de almacenamiento | Store at -20°C |
| Enviado en | Ice chest + Ice pads |
| Product Description | Bcl-2-IN-20 (Compound 81) is an inhibitor for Bcl-2 with IC 50 <10 μM (79.1% inhibition at 9 μM). Bcl-2-IN-20 exhibits cytotoxicity in SK-MEL-28 ( IC 50 >10 μM), A549 ( IC 50 =6.1 μM), HepG2 ( IC 50 >10 μM), MCF-7 ( IC 50 =8.9 μM), HCT116 ( IC 50 >10 μM) and HEK-293 ( IC 50 =14.1 μM). Bcl-2-IN-20 promotes the ROS production, induces apoptosis and DNA damage. |
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